Advances in Multimodality Imaging in Cardio-Oncology: JACC State-of-the-Art Review

LA Baldassarre, S Ganatra, J Lopez-Mattei… - Journal of the American …, 2022 - jacc.org
The population of patients with cancer is rapidly expanding, and the diagnosis and
monitoring of cardiovascular complications greatly rely on imaging. Numerous advances in …

Fixed-duration ibrutinib-venetoclax in patients with chronic lymphocytic leukemia and comorbidities

AP Kater, C Owen, C Moreno, G Follows… - NEJM …, 2022 - evidence.nejm.org
Background GLOW is a phase 3 trial evaluating the efficacy and safety of ibrutinib-
venetoclax in older patients and/or those with comorbidities with previously untreated …

[PDF][PDF] Ibrutinib-associated cardiotoxicity: from the pharmaceutical to the clinical

R Dong, Y Yan, X Zeng, N Lin, B Tan - Drug Design, Development …, 2023 - Taylor & Francis
Ibrutinib is the first-in-class Bruton tyrosine kinase (BTK) inhibitor that has revolutionized the
treatment of B cell malignancies. Unfortunately, increased incidences of cardiotoxicity have …

Cardiac fibrosis in oncologic therapies

RRS Packard - Current opinion in physiology, 2022 - Elsevier
Cardiotoxicity, or the development of unwarranted cardiovascular side-effects of oncologic
therapies, can involve all aspects of cardiovascular disease. The development of cardiac …

Diagnosis and management of cardiovascular effects of bruton's tyrosine kinase inhibitors

N Aghel, RC Baro Vila, M Lui, C Hillis… - Current Cardiology …, 2023 - Springer
Abstract Purpose of Review Bruton's tyrosine kinase inhibitors (BTKis) have changed the
treatment and prognosis of several B-cell malignancies. However, since the approval of the …

Cardiovascular events reported in patients with B-cell malignancies treated with zanubrutinib

JJ Moslehi, RR Furman, CS Tam, JE Salem… - Blood …, 2024 - ashpublications.org
First-generation Bruton tyrosine kinase (BTK) inhibitor, ibrutinib, has been associated with
an increased risk of cardiovascular toxicities. Zanubrutinib is a more selective, next …

Onco-hypertension: a continuously developing field between cancer and hypertension

S Totolici, AM Vrabie, E Badila, E Weiss - International Journal of …, 2024 - mdpi.com
The prognosis of cancer patients has greatly improved in the last years, owing to the
development of novel chemotherapeutic agents. However, this progress comes with an …

[HTML][HTML] Characterization of zanubrutinib safety and tolerability profile and comparison with ibrutinib safety profile in patients with B-cell malignancies: post hoc …

JR Brown, P Ghia, W Jurczak, BS Kahl… - …, 2024 - ncbi.nlm.nih.gov
Zanubrutinib is a next-generation Bruton tyrosine kinase inhibitor (BTKi) designed to
minimize off-target effects associated with toxicities that have limited long-term treatment …

Peripheral vascular disease in 2021

NJ Leeper, NM Hamburg - Circulation research, 2021 - Am Heart Assoc
It seems fitting in this year of isolation and pandemic to open the Compendium on Peripheral
Vascular Diseases with the voices of patients. Gertrude Campbell was a pioneer as the first …

Serine/threonine-protein kinase STK24 induces tumorigenesis by regulating the STAT3/VEGFA signaling pathway

S Lai, D Wang, W Sun, X Cao - Journal of Biological Chemistry, 2023 - ASBMB
Lung cancer is the most common cause of cancer-related death. Although anti-angiogenesis
therapy has been effective in the treatment of nonsmall cell lung cancer (NSCLC), drug …