Proteins carry out the most difficult tasks in living cells. They do so by interacting specifically
with other molecules. This requires that they fold to a unique, globular conformation that is …

A common limitation of recombinant protein production in bacteria is the formation of
insoluble protein aggregates known as inclusion bodies. The propensity of a given protein to …

Motivation: Protein insolubility is a major obstacle for many experimental studies. A
sequence-based prediction method able to accurately predict the propensity of a protein to …

Poor protein solubility is a common problem in high-resolution structural studies, formulation
of protein pharmaceuticals, and biochemical characterization of proteins. One popular …

Solubility of proteins on overexpression in Escherichia coli is a manifestation of the net effect
of several sequence‐dependent and sequence‐independent factors. This study aims to …

High concentration protein delivery is difficult to achieve for several protein pharmaceuticals
due to low solubility. In this review, we discuss different types of low protein solubility …

Motivation: Inclusion body formation has been a major deterrent for overexpression studies
since a large number of proteins form insoluble inclusion bodies when overexpressed in …

To address the anticipated global need for increased protein supply for human nutrition,
particularly for developing and underdeveloped regions, concerted efforts are required …

Oligosaccharides, in either free or bound forms, play crucial roles in a wide range of
biological processes. Increasing appreciation of their roles in cellular communication …

Protein solubility plays a major role and has strong implication in the proteomics. Predicting
the propensity of a protein to be soluble or to form inclusion body is a fundamental and not …