Selected biomarkers of depression: what are the effects of cytokines and inflammation?
S Harsanyi, I Kupcova, L Danisovic, M Klein - International journal of …, 2022 - mdpi.com
Depression is one of the leading mental illnesses worldwide and lowers the quality of life of
many. According to WHO, about 5% of the worldwide population suffers from depression …
many. According to WHO, about 5% of the worldwide population suffers from depression …
Molecular mechanisms underlying the antidepressant actions of arketamine: beyond the NMDA receptor
The discovery of robust antidepressant actions exerted by the N-methyl-D-aspartate receptor
(NMDAR) antagonist (R, S)-ketamine has been a crucial breakthrough in mood disorder …
(NMDAR) antagonist (R, S)-ketamine has been a crucial breakthrough in mood disorder …
A path toward precision medicine for neuroinflammatory mechanisms in Alzheimer's disease
Neuroinflammation commences decades before Alzheimer's disease (AD) clinical onset and
represents one of the earliest pathomechanistic alterations throughout the AD continuum …
represents one of the earliest pathomechanistic alterations throughout the AD continuum …
Polyphenols and neuroprotection: Therapeutic implications for cognitive decline
Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …
human health. Several preclinical studies have been conducted to provide a rationale for …
Diet and mental health: Review of the recent updates on molecular mechanisms
Over the last decades, there has been a substantial increase in the prevalence of mental
health disorders, including an increased prevalence of depression, anxiety, cognitive, and …
health disorders, including an increased prevalence of depression, anxiety, cognitive, and …
Ketamine and its metabolites: Potential as novel treatments for depression
K Zhang, Y Yao, K Hashimoto - Neuropharmacology, 2023 - Elsevier
Depression is a well-known serious mental illness, and the onset of treatment using
traditional antidepressants is frequently delayed by several weeks. Moreover, numerous …
traditional antidepressants is frequently delayed by several weeks. Moreover, numerous …
[HTML][HTML] Cytokine research in depression: principles, challenges, and open questions
H Himmerich, O Patsalos, N Lichtblau… - Frontiers in …, 2019 - frontiersin.org
Cytokines have been implicated in the pathology of depression. Currently, the evidence is
based on cross-sectional studies and meta-analytic research comparing blood …
based on cross-sectional studies and meta-analytic research comparing blood …
Depression, dementia and immune dysregulation
S Hayley, AM Hakim, PR Albert - Brain, 2021 - academic.oup.com
Major depression is a prevalent illness that increases the risk of several neurological
conditions. These include stroke, cardiovascular disease, and dementia including …
conditions. These include stroke, cardiovascular disease, and dementia including …
Microglia, lifestyle stress, and neurodegeneration
Recent years have witnessed a revolution in our understanding of microglia biology,
including their major role in the etiology and pathogenesis of neurodegenerative diseases …
including their major role in the etiology and pathogenesis of neurodegenerative diseases …
Pathways connecting late-life depression and dementia
C Linnemann, UE Lang - Frontiers in pharmacology, 2020 - frontiersin.org
Late-life depression is associated with significant cognitive impairment. Meta-analyses
showed that depression is associated with an increased risk for Alzheimer's disease (AD) …
showed that depression is associated with an increased risk for Alzheimer's disease (AD) …