Lipid Horizons: Recent Advances and Future Prospects in LBDDS for Oral Administration of Antihypertensive Agents

Preeti, S Sambhakar, R Malik, S Bhatia… - International Journal …, 2024 - Wiley Online Library
The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is
anticipated to bring about comprehensive transformations in the pharmaceutical field …

[PDF][PDF] Selected excipients in oral solid dosage form with dry extract of Pyrola rotundifolia L.

N DARZULI, L BUDNIAK… - International Journal of …, 2019 - researchgate.net
Objective: The aim of the present study was to select excipients in an oral solid dosage form
with a dry extract of round-leaved wintergreen (Pyrola rotundifolia L.) by using asymmetric …

A one-step twin-screw melt granulation with gelucire 48/16 and surface adsorbent to improve the solubility of poorly soluble drugs: effect of formulation variables on …

S Sarabu, VR Kallakunta, A Butreddy, KY Janga… - Aaps Pharmscitech, 2021 - Springer
Fenofibrate is an effective lipid-lowering drug; however, its poor solubility and high log p
(5.2) result in insufficient absorption from the gastrointestinal tract, leading to poor …

Development and characterization of fast-dissolving tablet formulations of glyburide based on solid self-microemulsifying systems

M Cirri, A Roghi, M Valleri, P Mura - European Journal of Pharmaceutics …, 2016 - Elsevier
The aim of this work was to develop effective fast-dissolving tablet formulations of glyburide,
endowed with improved dissolution and technological properties, investigating the actual …

[PDF][PDF] Design, formulation and in-vitro characterization of Irbesartan solid self-nanoemulsifying drug delivery system (S-SNEDDS) prepared using spray drying …

AM Nasr, AR Gardouh, HM Ghonaim… - J Chem Pharm …, 2016 - researchgate.net
The main objective of this study was to develop solid self-nanoemulsifying drug delivery
system (S-SNEDDS) of Irbesartan (IRB) for enhancement of its solubility and dissolution …

Cationic solid self micro emulsifying drug delivery system (SSMED) of losartan: Formulation development, characterization and in vivo evaluation

VM Katla, K Veerabrahma - Journal of Drug Delivery Science and …, 2016 - Elsevier
The objective of the study was to develop solid self micro emulsifying drug delivery system
(SSMED) for enhancement of oral bioavailability of losartan (LOS). Solubility of LOS in …

[PDF][PDF] Formulation and evaluation of gliclazide in vegetable oil-based self emulsifying delivery system

GF Balata - Journal of applied pharmaceutical science, 2018 - japsonline.com
Objectives: To formulate a poorly water-soluble, antidiabetic drug, gliclazide, in the
vegetable oil-based self-emulsifying delivery system (SEDDS), as a trial to improve its …

[PDF][PDF] Formulation and in vitro evaluation of solid-self-emulsifying drug delivery system (SEDDS) of glibenclamide

M Saifee, S Zarekar, VU Rao, Z Zaheer… - Am J Adv Drug …, 2013 - academia.edu
Aim of present study was to develop solid self micro emulsifying drug delivery system (S-
SEDDS) with Aerosil 200 for enhancement of dissolution rate of model drug Glibenclamide …

[PDF][PDF] Development of a novel solid self-nano-emulsifying osmotically controlled system of a centrally acting drug: preparation and in-vitro evaluation

SA El-Zahaby, MH Aboughaly, GA Abdelbary… - Inventi Impact …, 2016 - researchgate.net
Vinpocetine (VNP) is a nootropic agent used in cerebrovascular disorders and dementia. Its
bioavailability is irregular and irreproducible, due to its low solubility in the intestine and …

Advanced delivery of poorly water soluble drug atorvastatin by lipid based formulation

AS Deshmukh, VR Mahajan - Asian journal of pharmaceutical research …, 2015 - ajprd.com
Atorvastatin Calcium used to lower cholesterol level in plasma of body by competitive
inhibiting HMG-CoA reductase, the rate determining enzyme in cholesterol biosynthesis via …