Progress on Regulation of NLRP3 Inflammasome by Chinese Medicine in Treatment of Ulcerative Colitis

H Sun, Y Zhu - Chinese journal of integrative medicine, 2023 - Springer
Ulcerative colitis (UC) is a chronic, non-specific intestinal disease that not only affects the
quality of life of patients and their families but also increases the risk of colorectal cancer …

Integrative analysis revealed the role of glucagon-like peptide-2 in improving experimental colitis in mice by inhibiting inflammatory pathways, regulating glucose …

D Li, Y Gao, L Cui, Y Li, H Ling, X Tan… - Frontiers in Microbiology, 2023 - frontiersin.org
Introduction Ulcerative colitis (UC) is an inflammatory bowel disease characterized by
recurrent and remitting inflammation of the mucosa of the colon and rectum, the incidence of …

[HTML][HTML] Network pharmacology-based analysis of heat clearing and detoxifying drug JC724 on the treatment of colorectal cancer

HZ Tang, ZP Yang, S Lu, B Wang… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Heat-clearing and detoxifying drugs has protective effect on colorectal
cancer (CRC). Given the complicated features of Traditional Chinese medicine formulas …

P38α contributes to TNF‐α‐induced IL‐8 production in human gingival cells

D Mao, H Inoue, T Notomi, S Goda - BioFactors, 2023 - Wiley Online Library
Tumor necrosis factor‐alpha (TNF‐α) is a major inflammatory cytokine that induces
interleukin (IL)‐8 production. Although some studies have reported the involvement of the …

Huangqin Decoction Delays Progress of Colitis-Associated Carcinogenesis by Regulating Nrf2/HO-1 Antioxidant Signal Pathway in Mice

L Gu, H Li, L Gao, H Li, L Wei, C Pan, K Wu… - Chinese Journal of …, 2024 - Springer
Objective To investigate the effect of Huangqin Decoction (HQD) on nuclear factor erythroid
2 related-factor 2 (Nrf2)/heme oxygenase (HO-1) signaling pathway by inducing the colitis …

β-sitosterol improves the permeability of lung epithelial cells by inhibiting the NF-kB pathway

X Chen, J Chen, Y Ren, M Wang, Z Yang, W Zhang… - 2023 - researchsquare.com
Objective: To investigate the mechanism of the protective effect of beta-sitosterol (BS) on
sepsis-induced lung injury. METHODS: A mouse model of sepsis-induced lung injury was …

GLP-2 ameliorates DSS-induced ulcerative colitis in mice by inhibiting inflammatory pathways and regulating gut microbiota

D Li, Y Gao, L Cui, Y Li, H Ling, X Tan, H Xu - 2022 - researchsquare.com
Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by
recurrence and remission of colonic and rectal mucosal inflammation, and its incidence is …

[引用][C] Dongyue Li, Yanhong Gao, Lanrong Cui, Yang Li, Hao Ling, Xin Tan and Hongyu Xu

D Li, Y Gao, L Cui, Y Li - europepmc.org
Results: The results showed that GLP-could reduce the inflammation of UC mice, which may
be achieved by inhibiting the potential targets of NF-κB, and Janus kinase (JAK)/STAT …