Aggregation induced emission (AIE) photosensitizers have attracted great attention due to
their good performance in photodynamic therapy (PDT). However, the therapeutic effect of …

The reactive oxygen species (ROS)-mediated mechanism is the major cause underlying the
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …

BACKGROUND: Photodynamic therapy (PDT) is an established, minimally invasive
treatment for specific types of cancer. During PDT, reactive oxygen species (ROS) are …

Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

The generation of singlet oxygen (1O2) during photodynamic therapy is limited by the
precise cooperation of light, photosensitizer, and oxygen, and the therapeutic efficiency is …

Free radicals, usually containing one or more unpaired electrons, are extremely unstable
and highly reactive with other biological molecules. Recently, there has been increasing …

Organic/inorganic nanohybrids have attracted widespread interests due to their favorable
properties and promising applications in biomedical areas. Great efforts have been made to …

Tumor hypoxia is typically presented in the central region of solid tumors, which is mainly
caused by an inadequate blood flow and oxygen supply. In the conventional treatment of …

Photodynamic therapy (PDT) can be developed into an important arsenal against cancer; it
is a minimally invasive therapy, which is used in the treatment or/and palliation of a variety of …

Photodynamic therapy (PDT) shows great potential for tumor treatment owing to its high
spatiotemporal selectivity, minimal invasiveness and patient compliance. However, the …