Therapeutic potential of polyphenols and other micronutrients of marine origin

L Pereira, J Cotas - Marine drugs, 2023 - mdpi.com
Polyphenols are compounds found in various plants and foods, known for their antioxidant
and anti-inflammatory properties. Recently, researchers have been exploring the therapeutic …

Chitosan-based nano systems for natural antioxidants in breast cancer therapy

Y Herdiana, P Husni, S Nurhasanah, S Shamsuddin… - Polymers, 2023 - mdpi.com
Breast cancer is a major cause of death globally, accounting for around 13% of all deaths.
Chemotherapy, the common treatment for cancer, can have side effects that lead to the …

Impact of nanotechnology on the oral delivery of phyto-bioactive compounds

H Nsairat, Z Lafi, M Al-Sulaibi, L Gharaibeh, W Alshaer - Food Chemistry, 2023 - Elsevier
Nanotechnology is an advanced field that has remarkable nutraceutical and food
applications. Phyto-bioactive compounds (PBCs) play critical roles in promoting health and …

Preclinical pharmacokinetics-related pharmacological effects of orally administered polysaccharides from traditional Chinese medicines: a review

D Ye, Q Zhao, D Ding, BL Ma - International Journal of Biological …, 2023 - Elsevier
Polysaccharides (TCMPs) derived from traditional Chinese medicines (TCMs), such as
Ganoderma lucidum, Astragalus membranaceus, Lycium barbarum, and Panax ginseng, are …

Oral delivery of biomacromolecules by overcoming biological barriers in the gastrointestinal tract: an update

S Liu, X Wen, X Zhang, S Mao - Expert opinion on drug delivery, 2023 - Taylor & Francis
Introduction Biomacromolecules have proven to be an attractive choice for treating diseases
due to their properties of strong specificity, high efficiency, and low toxicity. Besides greatly …

[HTML][HTML] Commercially available cell-free permeability tests for industrial drug development: increased sustainability through reduction of in vivo studies

AC Jacobsen, S Visentin, C Butnarasu, PC Stein… - Pharmaceutics, 2023 - mdpi.com
Replacing in vivo with in vitro studies can increase sustainability in the development of
medicines. This principle has already been applied in the biowaiver approach based on the …

Oral administration as a potential alternative for the delivery of small extracellular vesicles

D Donoso-Meneses, AI Figueroa-Valdés, M Khoury… - Pharmaceutics, 2023 - mdpi.com
Small extracellular vesicles (sEVs) have burst into biomedicine as a natural therapeutic
alternative for different diseases. Considered nanocarriers of biological origin, various …

Exploring the permeability of Amphotericin B trough serum albumin dispersions and lipid nanocarriers for oral delivery

HR Marcelino, A Solgadi, M Chéron… - International Journal of …, 2023 - Elsevier
Amphotericin B (AmB) is a potent polyenic antifungal agent with leishmanicidal activity. Due
to its low solubility and permeability in the gastrointestinal tract, AmB is usually administered …

The management of Parkinson's disease: An overview of the current advancements in drug delivery systems

DD Nakmode, CM Day, Y Song, S Garg - Pharmaceutics, 2023 - mdpi.com
Parkinson's disease (PD) has significantly affected a large proportion of the elderly
population worldwide. According to the World Health Organization, approximately 8.5 million …

Enhanced Cellular Uptake and Transport of Bovine lactoferrin using pectin-and Chitosan-modified solid lipid nanoparticles

X Yao, C Bunt, M Liu, SY Quek, J Shaw, J Cornish… - Pharmaceutics, 2023 - mdpi.com
Aim: The aim of this project is to use pectin-and chitosan-modified solid lipid nanoparticles
for bovine lactoferrin to enhance its cellular uptake and transport. Methods: Solid lipid …