Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …

Background The COVID-19 pandemic has exerted a significant toll on the lives of people
who use opioids (PWUOs). At the same time, more flexible regulations around provision of …

Background Alcohol and drug use can have negative consequences on the health,
economy, productivity, and social aspects of communities. We aimed to use data from the …

Fentanyl is a powerful opioid anesthetic and analgesic, the use of which has caused an
increasing public health threat in the United States and elsewhere. Fentanyl was initially …

Drug use represents a significant burden to public health through disease, disability and
social problems, and policy makers are becoming increasingly interested in how to develop …

Opioid overdose is the leading cause of death for Americans 25 to 64 years of age, and
opioid use disorder affects> 2 million Americans. The epidemiology of opioid-associated out …

Abstract Background and Aims Naloxone access laws (NALs) have been suggested to be
an important strategy to reduce opioid‐related harm. We describe the evolution of NALs …

Background: Many people use opioids and are at risk of overdose. Naloxone is an opioid
antagonist used to counter the effects of opioid overdose. There is an increased availability …

Background New synthetic opioids (NSO) constitute one of the fastest-growing group of New
Psychoactive Substances, which emerged on the illicit drug marker in the second half of …

Purpose: Opioid abuse and overdose is a public health concern as it relates to increased
morbidity and mortality. This systematic review focuses on the application of take-home …