Over the past decade, an enormous number of studies (> 100) have focused on the role of
nitric oxide (NO) in myocardial ischemia. It is important to distinguish the function of NO in …

Myocardial ischemic/reperfusion (IR) injury is a global cardiovascular disease with high
mortality and morbidity. Therapeutic interventions for myocardial ischemia involve restoring …

l-Arginine is the substrate for nitric oxide production. Endothelium dysfunction could be
attributed to l-arginine deficiency or the presence of l-arginine endogenous inhibitors. This …

The present study investigated the protective effect of l-citrulline on gastric mucosal injury
induced by ischemia–reperfusion (IR) in rats. Under anesthesia, the celiac artery was …

Nitric oxide synthesized from l-arginine in cells has important salutary physiological roles,
but can also exert deleterious effects. Nitric oxide (NO) can ameliorate post-ischemic …

Ischemic postconditioning (IPoC) reduces lethal reperfusion injury under normal conditions,
but its effectiveness is blocked by hypercholesterolemia. The present study aimed to …

Background: We have evaluated the addition of L-arginine, a precursor of nitric oxide, to a
cardioplegic solution (named CRMBM) designed for long-term heart preservation …

Background. Posthypoxic cardiopathy is one of the risk factors for the development of
cardiovascular pathology (rhythm disturbances, vascular dystonia, etc.) in subsequent age …

Objectives: This study was designed to investigate the gastroprotective effect of L-citrulline
against gastric ischemia-reperfusion injury. Materials and Methods: Sodium pentobarbital …

The cardiovascular pleiotropic effects of statins and a Rho-kinase inhibitor (fasudil) could be
of interest to prevent myocardial ischemia reperfusion injury (MIRI). In the present study, we …