Treatment selection in first-line metastatic renal cell carcinoma—the contemporary treatment paradigm in the age of combination therapy: a review

V Navani, DYC Heng - JAMA oncology, 2022 - jamanetwork.com
Importance The treatment landscape of metastatic renal cell carcinoma has evolved rapidly
over the last decade. Recent combination approaches heralded by targeting immune …

Efficacy of VEGFR-TKIs plus immune checkpoint inhibitors in metastatic renal cell carcinoma patients with favorable IMDC prognosis

C Ciccarese, R Iacovelli, C Porta, G Procopio… - Cancer Treatment …, 2021 - Elsevier
Abstract Background Combinations of PD-1/PD-L1 immune checkpoint inhibitors (ICI) with
VEGFR-TKIs as first-line therapy significantly improve outcomes of metastatic renal cell …

Managing First-Line Metastatic Renal Cell Carcinoma: Favorable-Risk Disease

E Pan, D Urman, C Malvar… - Hematology/Oncology …, 2023 - hemonc.theclinics.com
This article focuses on favorable-risk metastatic renal cell carcinoma (mRCC) and its
management. Risk stratification of newly diagnosed mRCC is important for prognostication …

Combination therapies in patients with favorable risk metastatic renal cell Carcinoma: A Systematic Review and Meta-Analysis

H Bolek, E Yekedüz, Y Ürün - Cancer Treatment Reviews, 2023 - Elsevier
Introduction Immunotherapy (IO)-based combination therapies have emerged as the
standard of care for first-line treatment of metastatic renal cell carcinoma (mRCC) among …

Prognostic Models in Metastatic Renal Cell Carcinoma

A Lemelin, K Takemura, DYC Heng… - Hematology …, 2023 - hemonc.theclinics.com
In the past decades, there have been important changes in the treatment landscape for
metastatic renal cell carcinoma (mRCC). With this evolution in therapies, the overall survival …

External Validation of a Novel Risk Model in Patients With Favorable Risk Renal Cell Carcinoma Defined by International Metastatic Renal Cell Carcinoma Database …

E Yekedüz, S Karakaya, İ Ertürk, D Tural, G Uçar… - Clinical Genitourinary …, 2023 - Elsevier
Background A novel prognostic model was recommended for patients with metastatic RCC
(mRCC) by the International mRCC Database Consortium (IMDC). In this study, we aimed to …

First-Line Systemic Treatment Options for Advanced Renal Cell Carcinoma

Q Qin, J Brugarolas, H Hammers, T Zhang - … Multidisciplinary Treatment for …, 2023 - Springer
The treatment of advanced clear cell renal cell carcinoma (ccRCC) has undergone
significant changes over the last two decades, particularly with the development of …

Vascular endothelial growth factor Vascular endothelial growth factor receptor

R Proto-Oncogene - Integrating Multidisciplinary Treatment for …, 2023 - books.google.com
The 5-year survival rate for patients with localized kidney cancer has significantly increased
over the last decades; however, until recently, prognosis for patients with advanced disease …