Metabolic reprogramming is one of the main characteristics of malignant tumors, which is
due to the flexible changes of cell metabolism that can meet the needs of cell growth and …

Cancer drug resistance represents the main obstacle in cancer treatment. Drug-resistant
cancers exhibit complex molecular mechanisms to hit back therapy under pharmacological …

The resistance of tumor cells to therapy severely impairs the efficacy of treatment, leading to
recurrence and metastasis of various cancers. Clarifying the underlying mechanisms of …

The tumor microenvironment (TME), which is regulated by intrinsic oncogenic mechanisms
and epigenetic modifications, has become a research hotspot in recent years. Characteristic …

Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …

Ischemic stroke has become a serious public health problem that causes high rates of death
and disability. Bone marrow mesenchymal stem cell (BMSC)-derived exosomes have shown …

Abstract N6-methyladenosine (m6A) is a ubiquitous mRNA modification in eukaryotes. m6A
occurs through the action of methyltransferases, demethylases, and methylation-binding …

With the development of RNA modification research, the importance of N6-methyladenosine
(m6A) in tumors cannot be ignored. m6A promotes the self-renewal of tumor stem cells and …

Abstract N6-methyladenosine (m6A) methylation, the most prevalent and abundant RNA
modification in eukaryotes, has recently become a hot research topic. Several studies have …

Glycolytic reprogramming is one of the most important features of cancer and plays an
integral role in the progression of cancer. In cancer cells, changes in glucose metabolism …