[HTML][HTML] The role of lncRNA just proximal to XIST (JPX) in human disease phenotypes and RNA methylation: The novel biomarker and therapeutic target potential
Y Kuang, W Shen, H Zhu, H Huang, Q Zhou… - Biomedicine & …, 2022 - Elsevier
Increasing evidence suggests that long non-coding RNAs (lncRNAs) are closely related to
the initialization and development of human diseases. lncRNA just proximal to XIST (JPX) …
the initialization and development of human diseases. lncRNA just proximal to XIST (JPX) …
Luteolin Pretreatment Ameliorates Myocardial Ischemia/Reperfusion Injury by lncRNA‐JPX/miR‐146b Axis
T Xu, Y Zhang, G Liao, H Xuan, J Yin… - Analytical Cellular …, 2023 - Wiley Online Library
Background. In the present study, we aimed to find out whether luteolin (Lut) pretreatment
could ameliorate myocardial ischemia/reperfusion (I/R) injury by regulating the lncRNA just …
could ameliorate myocardial ischemia/reperfusion (I/R) injury by regulating the lncRNA just …
[HTML][HTML] Identification of STAM-binding protein as a target for the treatment of gemcitabine resistance pancreatic cancer in a nutrient-poor microenvironment
W Zhang, Z Xu, Y Du, T Liu, Z Xiong, J Hu, L Chen… - Cell Death & …, 2024 - nature.com
Pancreatic cancer (PC) is a highly malignant solid tumor whose resistance to gemcitabine
(GEM) chemotherapy is a major cause of poor patient prognosis. Although PC is known to …
(GEM) chemotherapy is a major cause of poor patient prognosis. Although PC is known to …
[HTML][HTML] Writers, readers, and erasers RNA modifications and drug resistance in cancer
D Chen, X Gu, Y Nurzat, L Xu, X Li, L Wu, H Jiao… - Molecular Cancer, 2024 - Springer
Drug resistance in cancer cells significantly diminishes treatment efficacy, leading to
recurrence and metastasis. A critical factor contributing to this resistance is the epigenetic …
recurrence and metastasis. A critical factor contributing to this resistance is the epigenetic …
[HTML][HTML] Small molecule inhibitors targeting m6A regulators
G Feng, Y Wu, Y Hu, W Shuai, X Yang, Y Li… - Journal of Hematology & …, 2024 - Springer
As the most common form of epigenetic regulation by RNA, N6 methyladenosine (m6A)
modification is closely involved in physiological processes, such as growth and …
modification is closely involved in physiological processes, such as growth and …
[HTML][HTML] Interplay Between m6A RNA Methylation and Regulation of Metabolism in Cancer
Y Mobet, X Liu, T Liu, J Yu, P Yi - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Methylation of adenosine in RNA to N6-methyladenosine (m6A) is widespread in eukaryotic
cells with his integral RNA regulation. This dynamic process is regulated by methylases …
cells with his integral RNA regulation. This dynamic process is regulated by methylases …
[HTML][HTML] Insights into the regulatory role of RNA methylation modifications in glioma
S Long, Y Yan, H Xu, L Wang, J Jiang, Z Xu… - Journal of Translational …, 2023 - Springer
Epitranscriptomic abnormalities, which are highly prevalent in primary central nervous
system malignancies, have been identified as crucial contributors to the development and …
system malignancies, have been identified as crucial contributors to the development and …
[HTML][HTML] Non-coding RNA-Mediated N6-Methyladenosine (m6A) deposition: A pivotal regulator of cancer, impacting key signaling pathways in carcinogenesis and …
The emergence of RNA modifications has recently been considered as critical post-
transcriptional regulations which governed gene expression. N 6-methyladenosine (m 6 A) …
transcriptional regulations which governed gene expression. N 6-methyladenosine (m 6 A) …
The role of RNA m6A modification in cancer glycolytic reprogramming
As one of the main characteristics of neoplasia, metabolic reprogramming provides nutrition
and energy to enhance cell proliferation and maintain environment homeostasis. Glycolysis …
and energy to enhance cell proliferation and maintain environment homeostasis. Glycolysis …
RNA m6A modifications regulate crosstalk between tumor metabolism and immunity
J Gu, H Cao, X Chen, XD Zhang… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
In recent years, m6A modifications in RNA transcripts have arisen as a hot topic in cancer
research. Indeed, a number of independent studies have elaborated that the m6A …
research. Indeed, a number of independent studies have elaborated that the m6A …