[HTML][HTML] The role of lncRNA just proximal to XIST (JPX) in human disease phenotypes and RNA methylation: The novel biomarker and therapeutic target potential

Y Kuang, W Shen, H Zhu, H Huang, Q Zhou… - Biomedicine & …, 2022 - Elsevier
Increasing evidence suggests that long non-coding RNAs (lncRNAs) are closely related to
the initialization and development of human diseases. lncRNA just proximal to XIST (JPX) …

Luteolin Pretreatment Ameliorates Myocardial Ischemia/Reperfusion Injury by lncRNA‐JPX/miR‐146b Axis

T Xu, Y Zhang, G Liao, H Xuan, J Yin… - Analytical Cellular …, 2023 - Wiley Online Library
Background. In the present study, we aimed to find out whether luteolin (Lut) pretreatment
could ameliorate myocardial ischemia/reperfusion (I/R) injury by regulating the lncRNA just …

[HTML][HTML] Identification of STAM-binding protein as a target for the treatment of gemcitabine resistance pancreatic cancer in a nutrient-poor microenvironment

W Zhang, Z Xu, Y Du, T Liu, Z Xiong, J Hu, L Chen… - Cell Death & …, 2024 - nature.com
Pancreatic cancer (PC) is a highly malignant solid tumor whose resistance to gemcitabine
(GEM) chemotherapy is a major cause of poor patient prognosis. Although PC is known to …

[HTML][HTML] Writers, readers, and erasers RNA modifications and drug resistance in cancer

D Chen, X Gu, Y Nurzat, L Xu, X Li, L Wu, H Jiao… - Molecular Cancer, 2024 - Springer
Drug resistance in cancer cells significantly diminishes treatment efficacy, leading to
recurrence and metastasis. A critical factor contributing to this resistance is the epigenetic …

[HTML][HTML] Small molecule inhibitors targeting m6A regulators

G Feng, Y Wu, Y Hu, W Shuai, X Yang, Y Li… - Journal of Hematology & …, 2024 - Springer
As the most common form of epigenetic regulation by RNA, N6 methyladenosine (m6A)
modification is closely involved in physiological processes, such as growth and …

[HTML][HTML] Interplay Between m6A RNA Methylation and Regulation of Metabolism in Cancer

Y Mobet, X Liu, T Liu, J Yu, P Yi - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Methylation of adenosine in RNA to N6-methyladenosine (m6A) is widespread in eukaryotic
cells with his integral RNA regulation. This dynamic process is regulated by methylases …

[HTML][HTML] Insights into the regulatory role of RNA methylation modifications in glioma

S Long, Y Yan, H Xu, L Wang, J Jiang, Z Xu… - Journal of Translational …, 2023 - Springer
Epitranscriptomic abnormalities, which are highly prevalent in primary central nervous
system malignancies, have been identified as crucial contributors to the development and …

[HTML][HTML] Non-coding RNA-Mediated N6-Methyladenosine (m6A) deposition: A pivotal regulator of cancer, impacting key signaling pathways in carcinogenesis and …

M Hashemi, P Daneii, MA Zandieh, R Raesi… - Non-coding RNA …, 2023 - Elsevier
The emergence of RNA modifications has recently been considered as critical post-
transcriptional regulations which governed gene expression. N 6-methyladenosine (m 6 A) …

The role of RNA m6A modification in cancer glycolytic reprogramming

Y Li, H Huang, S Wu, Y Zhou, T Huang… - Current Gene …, 2023 - ingentaconnect.com
As one of the main characteristics of neoplasia, metabolic reprogramming provides nutrition
and energy to enhance cell proliferation and maintain environment homeostasis. Glycolysis …

RNA m6A modifications regulate crosstalk between tumor metabolism and immunity

J Gu, H Cao, X Chen, XD Zhang… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
In recent years, m6A modifications in RNA transcripts have arisen as a hot topic in cancer
research. Indeed, a number of independent studies have elaborated that the m6A …