Patient-specific models link neurotransmitter receptor mechanisms with motor and visuospatial axes of Parkinson's disease
Parkinson's disease involves multiple neurotransmitter systems beyond the classical
dopaminergic circuit, but their influence on structural and functional alterations is not well …
dopaminergic circuit, but their influence on structural and functional alterations is not well …
A Multimodal Meta-Analytical Evidence of Functional and Structural Brain Abnormalities Across Alzheimer's Disease Spectrum
X Tang, Z Guo, G Chen, S Sun, S Xiao, P Chen… - Ageing Research …, 2024 - Elsevier
Background Numerous neuroimaging studies have reported that Alzheimer's disease (AD)
spectrum have been linked to alterations in intrinsic functional activity and cortical thickness …
spectrum have been linked to alterations in intrinsic functional activity and cortical thickness …
[HTML][HTML] Unraveling neurotransmitter changes in de novo GBA-related and idiopathic Parkinson's disease
J Ren, L Yan, H Zhou, C Pan, C Xue, J Wu… - Neurobiology of disease, 2023 - Elsevier
Background Presently, neurotransmitter deficits in GBA-related Parkinson's disease (GBA-
PD) and relationships with cognitive impairment are poorly understood. A better …
PD) and relationships with cognitive impairment are poorly understood. A better …
[HTML][HTML] Multimodal data fusion reveals functional and neurochemical correlates of Parkinson's disease
D Shi, S Wu, C Zhuang, Y Mao, Q Wang, H Zhai… - Neurobiology of …, 2024 - Elsevier
Background Neurotransmitter deficits and spatial associations among neurotransmitter
distribution, brain activity, and clinical features in Parkinson's disease (PD) remain unclear …
distribution, brain activity, and clinical features in Parkinson's disease (PD) remain unclear …
Functional networks of reward and punishment processing and their molecular profiles predicting the severity of young adult drinking
Alcohol misuse is associated with altered punishment and reward processing. Here, we
investigated neural network responses to reward and punishment and the molecular profiles …
investigated neural network responses to reward and punishment and the molecular profiles …
Deciphering Distinct Genetic Risk Factors for FTLD-TDP Pathological Subtypes via Whole-Genome Sequencing
C Pottier, F Kucukali, M Baker, A Batzler, GD Jenkins… - medRxiv, 2024 - medrxiv.org
Frontotemporal lobar degeneration with neuronal inclusions of the TAR DNA-binding protein
43 (FTLD-TDP) is a fatal neurodegenerative disorder with only a limited number of risk loci …
43 (FTLD-TDP) is a fatal neurodegenerative disorder with only a limited number of risk loci …