Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer

S Mirzaei, MH Gholami, A Zabolian, H Saleki… - Pharmacological …, 2021 - Elsevier
As a phenolic acid compound, caffeic acid (CA) can be isolated from different sources such
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …

[HTML][HTML] A review of caffeine's effects on cognitive, physical and occupational performance

TM McLellan, JA Caldwell, HR Lieberman - Neuroscience & Biobehavioral …, 2016 - Elsevier
Caffeine is consumed by over 80% of US adults. This review examines the effects caffeine
has on cognitive and physical function, since most real-world activities require complex …

[HTML][HTML] Covid-19 and the subsequent lockdown modified dietary habits of almost half the population in an Italian sample

F Scarmozzino, F Visioli - Foods, 2020 - mdpi.com
The Covid-19 pandemic led to lockdowns in several parts of the world and, hence, changed
some daily habits, including social interactions, the ability to perform sports, and—possibly …

[HTML][HTML] Neuroprotective effects of coffee bioactive compounds: a review

K Socała, A Szopa, A Serefko, E Poleszak… - International journal of …, 2020 - mdpi.com
Coffee is one of the most widely consumed beverages worldwide. It is usually identified as a
stimulant because of a high content of caffeine. However, caffeine is not the only coffee …

Coffee, caffeine, and health outcomes: an umbrella review

G Grosso, J Godos, F Galvano… - Annual review of …, 2017 - annualreviews.org
To evaluate the associations between coffee and caffeine consumption and various health
outcomes, we performed an umbrella review of the evidence from meta-analyses of …

Caffeine: cognitive and physical performance enhancer or psychoactive drug?

S Cappelletti, P Daria, G Sani… - Current …, 2015 - ingentaconnect.com
Caffeine use is increasing worldwide. The underlying motivations are mainly concentration
and memory enhancement and physical performance improvement. Coffee and caffeine …

The medicinal chemistry of caffeine

G Faudone, S Arifi, D Merk - Journal of medicinal chemistry, 2021 - ACS Publications
The purine alkaloid caffeine is the most widely consumed psychostimulant drug in the world
and has multiple beneficial pharmacological activities, for example, in neurodegenerative …

Complexity of coffee flavor: A compositional and sensory perspective

WB Sunarharum, DJ Williams, HE Smyth - Food research international, 2014 - Elsevier
For the consumer, flavor is arguably the most important aspect of a good coffee. Coffee
flavor is extremely complex and arises from numerous chemical, biological and physical …

Adenosine receptors as drug targets—what are the challenges?

JF Chen, HK Eltzschig, BB Fredholm - Nature reviews Drug discovery, 2013 - nature.com
Adenosine signalling has long been a target for drug development, with adenosine itself or
its derivatives being used clinically since the 1940s. In addition, methylxanthines such as …

Coffee: biochemistry and potential impact on health

IA Ludwig, MN Clifford, MEJ Lean, H Ashihara… - Food & function, 2014 - pubs.rsc.org
This review provides details on the phytochemicals in green coffee beans and the changes
that occur during roasting. Key compounds in the coffee beverage, produced from the …