Focal to bilateral tonic–clonic seizures are associated with widespread network abnormality in temporal lobe epilepsy

N Sinha, N Peternell, GM Schroeder, J de Tisi… - …, 2021 - Wiley Online Library
Objective Our objective was to identify whether the whole‐brain structural network
alterations in patients with temporal lobe epilepsy (TLE) and focal to bilateral tonic–clonic …

[HTML][HTML] Altered brain network organization in adults with Asperger's syndrome: decreased connectome transitivity and assortativity with increased global efficiency

N Javaheripour, G Wagner, F de la Cruz… - Frontiers in …, 2023 - frontiersin.org
Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder that persists
into adulthood with both social and cognitive disturbances. Asperger's syndrome (AS) was a …

Ethyl pyruvate improves white matter remodeling in rats after traumatic brain injury

L Mao, L Sun, J Sun, B Sun, Y Gao… - CNS Neuroscience & …, 2021 - Wiley Online Library
Background Severe traumatic brain injury (TBI) results in long‐term neurological deficits
associated with white matter injury (WMI). Ethyl pyruvate (EP) is a simple derivative of the …

[HTML][HTML] Structural brain network deviations predict recovery after traumatic brain injury

JJ Gugger, N Sinha, Y Huang, AE Walter, C Lynch… - NeuroImage: Clinical, 2023 - Elsevier
Objective Traumatic brain injury results in diffuse axonal injury and the ensuing maladaptive
alterations in network function are associated with incomplete recovery and persistent …

The current state of functional MR imaging for trauma prognostication

D Ryan, S Mirbagheri… - Neuroimaging …, 2023 - neuroimaging.theclinics.com
Traumatic brain injury (TBI) has the largest influence on morbidity and mortality in trauma
patients. 1 Mildto-moderate concussive injuries affect more than 69 million people …

Structural-and-dynamical similarity predicts compensatory brain areas driving the post-lesion functional recovery mechanism

P Chakraborty, S Saha, G Deco… - Cerebral Cortex …, 2023 - academic.oup.com
The focal lesion alters the excitation–inhibition (E–I) balance and healthy functional
connectivity patterns, which may recover over time. One possible mechanism for the brain to …

[HTML][HTML] Volumetric and structural connectivity abnormalities co-localise in TLE

JJ Horsley, GM Schroeder, RH Thomas, J de Tisi… - NeuroImage: Clinical, 2022 - Elsevier
Patients with temporal lobe epilepsy (TLE) exhibit both volumetric and structural connectivity
abnormalities relative to healthy controls. How these abnormalities inter-relate and their …

Patient-Centered Approaches to Cognitive Assessment in Acute TBI

LW Johnson, C Prenshaw, A Corbin - Current Neurology and …, 2023 - Springer
Abstract Purpose of the Review The purpose of this article is to help clinicians understand
how underlying pathophysiologies and medical comorbidities associated with acute …

GABAA receptor subunit modulation reversed electrophysiological network alterations after blast exposure in rat organotypic hippocampal slice cultures

N Varghese, NE Amelinez-Robles, B Morrison III - Experimental Neurology, 2023 - Elsevier
Throughout training and deployment, some military service members are frequently exposed
to shock waves due to blasts, and some complain of myriad neurological symptoms. In rat …

Self-reported concussion history is not related to cortical volume in college athletes.

DH Schultz, HC Bouchard, MC Barbot… - medRxiv, 2024 - medrxiv.org
The long-term consequences of concussion are still being uncovered but have been linked
to disruptions in cognition and psychological well-being. Previous studies focusing on the …