Plant secondary metabolites as anticancer agents: successes in clinical trials and therapeutic application

AML Seca, DCGA Pinto - International journal of molecular sciences, 2018 - mdpi.com
Cancer is a multistage process resulting in an uncontrolled and abrupt division of cells and
is one of the leading causes of mortality. The cases reported and the predictions for the near …

Anticancer medicinal plants used by Moroccan people: Ethnobotanical, preclinical, phytochemical and clinical evidence

IA Merrouni, M Elachouri - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Cancer is a major health problem worldwide. Drugs' side
effects and high cost of treatment remain the main limitations of conventional therapy …

[HTML][HTML] Ethnopharmacological study of natural products used for traditional cancer therapy in Algeria

K Taïbi, LA Abderrahim, K Ferhat, S Betta… - Saudi Pharmaceutical …, 2020 - Elsevier
Traditional and complementary medicine constitutes an important, and often
underestimated, source of healthcare for multiple diseases including cancer. However, little …

Indigenous knowledge of the traditional use of aromatic and medicinal plants in Rif Mountains Ketama District

Y El-Mernissi, A Zouhri, A Labhar… - Evidence‐Based …, 2023 - Wiley Online Library
Background. Medicinal plants have long played an integral role in traditional healing
systems and are crucial for meeting primary healthcare needs. This study aimed to …

Cytotoxicity of the methanol extracts and compounds of Brucea antidysenterica (Simaroubaceae) towards multifactorial drug-resistant human cancer cell lines

LM Youmbi, YSD Makong, AT Mbaveng… - … Medicine and Therapies, 2023 - Springer
Background Cancer remains a global health concern and constitutes an important barrier to
increasing life expectancy. Malignant cells rapidly develop drug resistance leading to many …

Ethnopharmacological Survey of Herbal Remedies Used for the Treatment of Cancer in the Greater Casablanca‐Morocco

M Bourhia, A Abdelaziz Shahat… - Evidence‐Based …, 2019 - Wiley Online Library
Medicinal plants played an important role in traditional medicine for the treatment of
diseases since antiquities. The aim of the study is to carry out an ethnobotanical survey on …

A comprehensive review on pharmacological activities of pachypodol: A bioactive compound of an aromatic medicinal plant Pogostemon cablin Benth

S Fatima, I Farzeen, A Ashraf, B Aslam, MU Ijaz… - Molecules, 2023 - mdpi.com
As is well known, plant products have been increasingly utilized in the pharmaceutical
industry in recent years. By combining conventional techniques and modern methodology …

A review on traditionally used South African medicinal plants, their secondary metabolites and their potential development into anticancer agents

D Twilley, S Rademan, N Lall - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Approximately 70% of anticancer drugs were developed
or derived from natural products or plants. Southern Africa boasts an enormous floral …

Pentacyclic triterpenoids with nitrogen-containing heterocyclic moiety, privileged hybrids in anticancer drug discovery

V Khwaza, S Mlala, OO Oyedeji, BA Aderibigbe - Molecules, 2021 - mdpi.com
Pentacyclic triterpenoids are well-known phytochemicals with various biological activities
commonly found in plants as secondary metabolites. The wide range of biological activities …

Prediction of potential cancer-related molecular targets of North African plants constituents using network pharmacology-based analysis

E Shawky - Journal of ethnopharmacology, 2019 - Elsevier
Ethnopharmacological relevance Nowadays, cancer is considered one of the leading
causes of death in developing countries. Due to mediocre socioeconomic status of many of …