The rising crisis of illicit fentanyl use, overdose, and potential therapeutic strategies

Y Han, W Yan, Y Zheng, MZ Khan, K Yuan… - Translational psychiatry, 2019 - nature.com
Fentanyl is a powerful opioid anesthetic and analgesic, the use of which has caused an
increasing public health threat in the United States and elsewhere. Fentanyl was initially …

The evolving overdose epidemic: synthetic opioids and rising stimulant-related harms

CM Jones, F Bekheet, JN Park… - Epidemiologic …, 2020 - academic.oup.com
The opioid overdose epidemic is typically described as having occurred in 3 waves, with
morbidity and mortality accruing over time principally from prescription opioids (1999–2010) …

Racial/ethnic and geographic trends in combined stimulant/opioid overdoses, 2007–2019

T Townsend, D Kline, A Rivera-Aguirre… - American journal of …, 2022 - academic.oup.com
Abstract In the United States, combined stimulant/opioid overdose mortality has risen
dramatically over the last decade. These increases may particularly affect non-Hispanic …

The rise in non‐fatal and fatal overdoses involving stimulants with and without opioids in the United States

B Hoots, A Vivolo‐Kantor, P Seth - Addiction, 2020 - Wiley Online Library
Aims To examine trends and recent changes in non‐fatal and fatal stimulant overdose rates
with and without opioids to improve the descriptive characterization of the US overdose …

Cocaine use and overdose mortality in the United States: Evidence from two national data sources, 2002–2018

M Cano, S Oh, CP Salas-Wright, MG Vaughn - Drug and alcohol …, 2020 - Elsevier
Background Cocaine-involved overdose mortality has recently risen in the United States
(US), yet it is unclear to what extent patterns in cocaine-involved overdose mortality parallel …

Rate of fentanyl positivity among urine drug test results positive for cocaine or methamphetamine

L LaRue, RK Twillman, E Dawson, P Whitley… - JAMA Network …, 2019 - jamanetwork.com
Importance Drug overdose deaths continue to increase, despite the leveling off of
prescription opioid use and policy changes limiting opioid prescribing. Illicit fentanyl is the …

New drugs, old targets: tweaking the dopamine system to treat psychostimulant use disorders

AH Newman, T Ku, CJ Jordan… - Annual review of …, 2021 - annualreviews.org
The abuse of illicit psychostimulants such as cocaine and methamphetamine continues to
pose significant health and societal challenges. Despite considerable efforts to develop …

The practice and embodiment of “goofballs”: a qualitative study exploring the co-injection of methamphetamines and opioids

A Ivsins, T Fleming, A Barker, M Mansoor… - International Journal of …, 2022 - Elsevier
Background Polysubstance use is common among people who use drugs, including the co-
use of stimulants and opioids. Research suggests the practice of simultaneous co-injection …

Racial/ethnic differences in US drug overdose mortality, 2017–2018

M Cano - Addictive behaviors, 2021 - Elsevier
Background The year 2018 marked the first year since 1999 in which the number of drug
overdose deaths in the United States (US) declined compared to the previous year …

[HTML][HTML] Understanding intentionality of fentanyl use and drug overdose risk: findings from a mixed methods study of people who inject drugs in New York City

C McKnight, CA Weng, M Reynoso, S Kimball… - International Journal of …, 2023 - Elsevier
Background As the proportion of drug overdose deaths involving fentanyl continues to
increase in the US, monitoring exposure to and possible changes in intention to use fentanyl …