[HTML][HTML] γδ T cells: origin and fate, subsets, diseases and immunotherapy
Y Hu, Q Hu, Y Li, L Lu, Z Xiang, Z Yin… - … and Targeted Therapy, 2023 - nature.com
The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …
hyperactivation, highlights the potential of immune renormalization as a promising strategy …
The immunopathogenesis of narcolepsy type 1
Abstract Narcolepsy type 1 (NT1) is a chronic sleep disorder resulting from the loss of a
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …
[HTML][HTML] Algae-Derived Natural Products in Diabetes and Its Complications—Current Advances and Future Prospects
L Pereira, A Valado - Life, 2023 - mdpi.com
Diabetes poses a significant global health challenge, necessitating innovative therapeutic
strategies. Natural products and their derivatives have emerged as promising candidates for …
strategies. Natural products and their derivatives have emerged as promising candidates for …
Assessment of the Negative Factors for the Clinical Outcome in Patients with SARS-CoV-2 Infection and Type 2 Diabetes Mellitus
Purpose Patients with diabetes mellitus (DM) are more susceptible to viral and bacterial
infections, facing a more severe prognosis and higher mortality rates. The study's main aim …
infections, facing a more severe prognosis and higher mortality rates. The study's main aim …
Glyburide-treated human monocyte-derived dendritic cells loaded with insulin represent tolerogenic features with anti-inflammatory responses and modulate …
Tolerogenic dendritic cells (TolDCs) are attractive therapeutic options for autoimmune
disorders because they suppress autologous T-cell responses. Dendritic cells (DCs) are …
disorders because they suppress autologous T-cell responses. Dendritic cells (DCs) are …
[HTML][HTML] Association between gut microbiota and onset of type 2 diabetes mellitus: a two-sample Mendelian randomization study
H Zhang, L Ma, W Peng, B Wang, Y Sun - Frontiers in cellular and …, 2024 - frontiersin.org
Aim Mendelian randomization (MR) analysis has been used in the exploration of the role of
gut microbiota (GM) in type 2 diabetes mellitus (T2DM); however, it was limited to the genus …
gut microbiota (GM) in type 2 diabetes mellitus (T2DM); however, it was limited to the genus …
[HTML][HTML] A human 3D immune competent full-thickness skin model mimicking dermal dendritic cell activation
JM Hölken, K Friedrich, M Merkel, N Blasius… - Frontiers in …, 2023 - frontiersin.org
We have integrated dermal dendritic cell surrogates originally generated from the cell line
THP-1 as central mediators of the immune reaction in a human full-thickness skin model …
THP-1 as central mediators of the immune reaction in a human full-thickness skin model …
[HTML][HTML] In Silico Design, Synthesis, and Evaluation of Novel Enantiopure Isoxazolidines as Promising Dual Inhibitors of α-Amylase and α-Glucosidase
Isoxazolidine derivatives were designed, synthesized, and characterized using different
spectroscopic techniques and elemental analysis and then evaluated for their ability to …
spectroscopic techniques and elemental analysis and then evaluated for their ability to …
The implications of the pandemic with Covid-19 in the glycemic control of people with type 2 diabetes
A Gherbon, M Frandes, M Nicula-Neagu… - Diabetes, Metabolic …, 2023 - Taylor & Francis
Introduction The COVID-19 lockdown influenced the glycemic control and other metabolic
parameters in people with type 1 and 2 diabetes mellitus. Objective To study the effects of …
parameters in people with type 1 and 2 diabetes mellitus. Objective To study the effects of …
[HTML][HTML] Prevalence of autoimmune diseases in an admixed population of patients with type 1 diabetes: a multicenter study in Brazil
MB Gomes, FO Braga, KG Drummond… - Diabetology & Metabolic …, 2024 - Springer
Background/objectives The primary aim of this study was to evaluate the prevalence of
autoimmune diseases (AIDs) and its associated factors in an admixed Brazilian population …
autoimmune diseases (AIDs) and its associated factors in an admixed Brazilian population …