Palytoxin-group toxins (PlTX) exert their potent biological activity by altering mechanisms of
ion homeostasis in excitable and non-excitable tissues. This review will describe major …

Phycotoxins are natural metabolites produced by micro-algae. Through accumulation in the
food chain, these toxins may concentrate in different marine organisms, including filter …

Palytoxin, isolated from a zoanthid of the genus Palythoa, is the most potent marine toxin
known. Intoxication by palytoxin leads to vasoconstriction, hemorrhage, ataxia, muscle …

Palytoxin (PlTX) is one of the largest compound present in nature and, with its strong ability
to modify the normal function of different biological systems, is also classified as one of the …

The oceans cover nearly 69) of the whole surface area of the earth and more than 29
phylums and 499999 species of marine organisms live in them [In the oceans the …

The major physiological function of parathyroid hormone (PTH) is the maintenance of Ca
2+/P i homeostasis via the parathyroid hormone/parathyroid hormone-related protein …

Palytoxin (PTX) is known to bind to Na, K-ATPase, to inhibit its activity, and to induce cation
conductance, but the mechanism of these effects is still poorly understood. In Xenopus …

Palytoxin (PTX) is a potent marine phycotoxin that binds to the Na, K-ATPase, converting this
pump into an open channel. We have recently shown (Vale et al., 2006) that PTX causes an …

Abstract The EFSA Panel on Contaminants in the Food Chain (CONTAM Panel) assessed
the risks to human health related to the presence of palytoxin (PlTX)‐group toxins in …

The early work of Drs. Philip Helfrich, Paul Scheuer, Alfred Banner, and others at the
University of Hawaii in the early 1960s on their newly discovered compound that was soon …