Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

Generalized anxiety disorder (GAD) is characterized by excessive worry about a variety of
topics. In addition to the presence of uncontrollable and persistent worry, the diagnosis of …

The objective of this study was to evaluate the effect of pharmacogenetics-guided treatment
on patients diagnosed with depression and/or anxiety, in a diverse set of clinical settings, as …

Abstract Serotonin (5-HT) 2C receptors play an important role in the modulation of
monoaminergic transmission, mood, motor behaviour, appetite and endocrine secretion …

OBJECTIVE To review pregabalin's pharmacology, pharmacokinetics, efficacy, and adverse
effects in the treatment of neuropathic pain, epilepsy, and anxiety. DATA SOURCES A …

Introduction: Modest response and remission rates for the selective serotonin reuptake
inhibitors and the serotonin-norepinephrine reuptake inhibitors, coupled with mounting …

This study examined the efficacy and tolerability of duloxetine 60–120 mg/day for the
treatment of patients with generalized anxiety disorder. This was a multicenter, randomized …

Generalized anxiety disorder (GAD), a prevalent and chronic illness, is associated with
dysregulation in both serotonergic and noradrenergic neurotransmission. Our study …

No systematic review or meta-analysis using a hard outcome has been conducted on the
role of benzodiazepines for generalized anxiety disorder (GAD). The objective of this study …

During recent years growing attention has been paid to psychiatric comorbidities in epilepsy.
However, anxiety disorders still remain underrecognized and undertreated. This is largely …