[HTML][HTML] Pyroptosis in health and disease: mechanisms, regulation and clinical perspective
Y Liu, R Pan, Y Ouyang, W Gu, T Xiao… - … and Targeted Therapy, 2024 - nature.com
Pyroptosis is a type of programmed cell death characterized by cell swelling and osmotic
lysis, resulting in cytomembrane rupture and release of immunostimulatory components …
lysis, resulting in cytomembrane rupture and release of immunostimulatory components …
Harnessing Pyroptosis for Lung Cancer Therapy: The Impact of NLRP3 Inflammasome Activation
Lung cancer is still a global health challenge in terms of high incidence, morbidity, and
mortality. Recent scientific studies have determined that pyroptosis, a highly inflammatory …
mortality. Recent scientific studies have determined that pyroptosis, a highly inflammatory …
[HTML][HTML] A nomogram based on the expression level of angiopoietin-like 4 to predict the severity of community-acquired pneumonia
S Chen, J Jiang, M Su, P Chen, X Liu, W Lei… - BMC Infectious …, 2023 - Springer
Background The morbidity and mortality of community-acquired pneumonia (CAP) remain
high among infectious diseases. It was reported that angiopoietin-like 4 (ANGPTL4) could …
high among infectious diseases. It was reported that angiopoietin-like 4 (ANGPTL4) could …
Systems Biology for Drug Target Discovery in Acute Myeloid Leukemia
S Novikova, T Tolstova, L Kurbatov… - International Journal of …, 2024 - mdpi.com
Combining new therapeutics with all-trans-retinoic acid (ATRA) could improve the efficiency
of acute myeloid leukemia (AML) treatment. Modeling the process of ATRA-induced …
of acute myeloid leukemia (AML) treatment. Modeling the process of ATRA-induced …
[HTML][HTML] Immunonutrition, Metabolism, and Programmed Cell Death in Lung Cancer: Translating Bench to Bedside
P Fedele, AN Santoro, F Pini, M Pellegrino, G Polito… - Biology, 2024 - mdpi.com
Simple Summary Lung cancer presents significant therapeutic challenges, driving the
exploration of novel treatment strategies. Programmed cell death (PCD) mechanisms …
exploration of novel treatment strategies. Programmed cell death (PCD) mechanisms …
Angiopoietin-Related Protein 4-Transcript 3 Increases the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma Cells and Inhibits Apoptosis
Y Bai, G Cui, X Sun, M Wei, Y Liu, J Guo… - DNA and Cell …, 2024 - liebertpub.com
To investigate the functional differences of angiopoietin-related protein 4 (ANGPTL4)
transcripts in hepatocellular carcinoma (HCC) cells. By transfecting ANGPTL4-Transcript 1 …
transcripts in hepatocellular carcinoma (HCC) cells. By transfecting ANGPTL4-Transcript 1 …
[HTML][HTML] ANGPTL4, a direct target of hsa-miR-133a-3p, accelerates lung adenocarcinoma lipid metabolism, proliferation and invasion
Q Hu, S Chen, Y Li, T Hu, J Hu, C Wang, F Yang… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Background: Globally, lung adenocarcinoma (LUAD) is the most common type of lung
cancer. The secreted protein angiopoietin-like 4 (ANGPTL4) has been implicated in a …
cancer. The secreted protein angiopoietin-like 4 (ANGPTL4) has been implicated in a …
ANGPTL4 Stabilizes Bone Morphogenetic Protein 7 Through Deubiquitination and Promotes HCC Proliferation via the SMAD/MAPK Pathway
Y Bai, G Cui, X Sun, M Wei, Y Liu, J Guo… - DNA and Cell …, 2024 - liebertpub.com
This study aimed to determine the function of angiopoietin-related protein 4 (ANGPTL4) and
bone morphogenetic protein 7 (BMP7) on hepatocellular carcinoma (HCC). Overexpressing …
bone morphogenetic protein 7 (BMP7) on hepatocellular carcinoma (HCC). Overexpressing …
GNB4 Silencing Promotes Pyroptosis to Inhibit the Development of Glioma by Activating cGAS–STING Pathway
Z Gao, J Yang - Molecular Biotechnology, 2024 - Springer
The induction of immunogenic cell death is a promising therapeutic option for gliomas.
Pyroptosis is a type of programmed immunogenic cell death and its role in gliomas remains …
Pyroptosis is a type of programmed immunogenic cell death and its role in gliomas remains …
[HTML][HTML] Anoikis-related subtype and prognosis analyses based on bioinformatics, and an expression verification of ANGPTL4 based on experiments of lung …
X Shen, J Xie, S Liu, Y Cai, S Yuan… - Journal of Thoracic …, 2024 - jtd.amegroups.org
Background: Lung adenocarcinoma (LUAD) is one of the most common malignant tumors
with high mortality. Anoikis resistance is an important mechanism of tumor cell proliferation …
with high mortality. Anoikis resistance is an important mechanism of tumor cell proliferation …