Lung cancer: Biology and treatment options

H Lemjabbar-Alaoui, OUI Hassan, YW Yang… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Lung cancer remains the leading cause of cancer mortality in men and women in the US
and worldwide. About 90% of lung cancer cases are caused by smoking and the use of …

Pathogenesis of lung cancer: 100 year report

YE Miller - American journal of respiratory cell and molecular …, 2005 - atsjournals.org
Over the past 100 years, our understanding of the pathogenesis of lung cancer has
advanced impressively. Environmental carcinogens and a gene locus determining …

The molecular basis of lung cancer: molecular abnormalities and therapeutic implications

PP Massion, DP Carbone - Respiratory research, 2003 - Springer
Lung cancer is the number one cause of cancer-related death in the western world. Its
incidence is highly correlated with cigarette smoking, and about 10% of long-term smokers …

New molecularly targeted therapies for lung cancer

S Sun, JH Schiller, M Spinola… - The Journal of clinical …, 2007 - Am Soc Clin Investig
Lung cancer is the leading cause of cancer death worldwide. The disease is particularly
difficult to detect, and patients often present at an advanced stage. Current treatments have …

Molecular pathology of lung cancer: current status and perspectives

F Oberndorfer, L Müllauer - Current opinion in oncology, 2018 - journals.lww.com
The discoveries of cancer research have been translated into the clinical management of
lung cancer patients. So far, the approach of targeted therapy that is directed towards certain …

The biology of lung cancer: development of more effective methods for prevention, diagnosis, and treatment

R Salehi-Rad, R Li, MK Paul… - Clinics in chest …, 2020 - chestmed.theclinics.com
Lung cancer is the leading cause of cancer-related death worldwide. Approximately 15% of
lung cancers have the histologic subtype of small cell lung cancer (SCLC) and the …

Molecular biology of lung cancer: clinical implications

JE Larsen, JD Minna - Clinics in chest medicine, 2011 - chestmed.theclinics.com
Lung cancer is the leading cause of cancer-related death in men and women in the United
States, accounting for approximately 28% of total cancer deaths in 2010 despite comprising …

[HTML][HTML] Molecular pathways and therapeutic targets in lung cancer

E Shtivelman, T Hensing, GR Simon, PA Dennis… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Lung cancer is still the leading cause of cancer death worldwide. Both histologically and
molecularly lung cancer is heterogeneous. This review summarizes the current knowledge …

Lung cancer: progress in diagnosis, staging and therapy

SG Spiro, NT Tanner, GA Silvestri, SM Janes… - …, 2010 - Wiley Online Library
Lung cancer remains one of the greatest medical challenges with nearly 1.5 million new
cases worldwide each year and a growing tobacco epidemic in the developing world. This …

Focus on lung cancer

JD Minna, JA Roth, AF Gazdar - Cancer cell, 2002 - cell.com
Lung cancer is the most common form of cancer in the world (12.3% of all cancers), with an
estimated 1.2 million new cases in 2000 (Parkin et al., 2001). Tobacco smoking is the most …