Protective effects of sinomenine against dextran sulfate sodium-induced ulcerative colitis in rats via alteration of HO-1/Nrf2 and inflammatory pathway

Z Niu, X Li, X Yang, Z Sun - Inflammopharmacology, 2024 - Springer
Background Dextran Sulfate Sodium (DSS) induces ulcerative colitis (UC), a type of
inflammatory bowel disease (IBD) that leads to inflammation, swelling, and ulcers in the …

Sinomenine hydrochloride ameliorates dextran sulfate sodium‑induced colitis in mice by modulating the gut microbiota composition whilst suppressing the activation …

Y Zhou, S Chen, W Gu, X Sun… - Experimental and …, 2021 - spandidos-publications.com
Sinomenine is a pure alkaloid that can be isolated from the root of Sinomenium acutum and
has been found to exert anti‑inflammatory and immunosuppressive effects. The present …

Sinomenine alleviates dextran sulfate sodium‑induced colitis via the Nrf2/NQO‑1 signaling pathway

Y Zhou, H Liu, J Song, L Cao… - Molecular medicine …, 2018 - spandidos-publications.com
Sinomenine (SIN), a pure alkaloid isolated from Sinomenium acutum, has been widely used
in arthritis for its anti‑inflammatory effect, but little is known about the effect of SIN on human …

Sinomenine attenuated dextran sulfate sodium-induced inflammatory responses by promoting 14-3-3θ protein and inhibiting NF-κB signaling

Y Zhou, S Chen, Y Dai, L Wu, M Jin, J Zhao, Y Li… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance The rhizome of Chinese medical plant QingTeng (scientific
name: Sinomenium acutum (Thunb.) Rehd. et Wils.) is widely used by traditional medical …

Sericic Acid Ameliorates DSS-induced Ulcerative Colitis in Mice by Modulating the NF-ΚB and Nrf2 Pathways

J Zhang, X Li, Y Zhu, Y Wang… - Current Molecular …, 2023 - ingentaconnect.com
Background: Ulcerative colitis (UC) is a chronic non-specific inflammatory bowel disease. In
previous studies, we found extracts from the roots of Rosa odorata Sweet var. gigantea (Coll …

Timosaponin BⅡ reduces colonic inflammation and alleviates DSS-induced ulcerative colitis by inhibiting NLRP3

M Feng, Y Zhou, Z Gao, W Huang, W Xie, W Xie… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance The Timosaponin BⅡ (TBⅡ) is one of the main
active components of the traditional Chinese medicine Anemarrhena asphodeloides, and it …

[HTML][HTML] Protection against dextran sulfate sodium-induced ulcerative colitis in mice by neferine, a natural product from Nelumbo nucifera Gaertn

X Min, Y Guo, Y Zhou, X Chen - Cell Journal (Yakhteh), 2021 - ncbi.nlm.nih.gov
Objective Ulcerative colitis (UC) is a long-lasting inflammatory disease of the colon.
Epidemiological studies showed that the prevalence and incidence of UC are increasing …

Wogonoside protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB and NLRP3 inflammasome activation

Y Sun, Y Zhao, J Yao, L Zhao, Z Wu, Y Wang… - Biochemical …, 2015 - Elsevier
Previous studies have demonstrated that wogonoside, the glucuronide metabolite of
wogonin, has anti-inflammatory, anti-angiogenic and anticancer effects. However, the anti …

Natural naphthoquinones isolated from Lithospermum erythrorhizon suppress dextran sulfate sodium-induced murine experimental colitis

W Sun, H Han, Z Wang, Z Wen, M Yang, Y Wang, J Fu… - bioRxiv, 2019 - biorxiv.org
The purpose of this study was to explore the effects of natural shikonin and its derivatives on
mice experimental colitis induced by dextran sulfate sodium, and to investigate the …

Sanguinarine protects against indomethacin-induced small intestine injury in rats by regulating the Nrf2/NF-κB pathways

X Lin, Y Shi, Y Cao, X Tan, Y Zeng, S Luo… - Frontiers in …, 2022 - frontiersin.org
In recent years, small intestine as a key target in the treatment of Inflammatory bowel
disease caused by NSAIDs has become a hot topic. Sanguinarine (SA) is one of the main …