Heparan sulphate is an important mediator in determining vascular smooth muscle cell
(SMC) phenotype. The sulphation pattern of the heparan sulphate chains is critical to their …

Heparan sulphate N-deacetylase/N-sulphotransferase (NDST) enzymes catalyse the
reaction that initiates sulphation and subsequent modification of the oligosaccharide …

Heparan sulfate proteoglycans are abundant molecules in the extracellular matrix and at the
cell surface. Heparan sulfate chains are composed of groups of disaccharides whose side …

Heparan sulfate proteoglycans act as co-receptors for many chemokines and growth factors.
The sulfation pattern of the heparan sulfate chains is a critical regulatory step affecting the …

N-Deacetylation andN-sulfation of N-acetylglucosamine residues in heparan sulfate and
heparin initiate a series of chemical modifications that ultimately lead to oligosaccharide …

Analysis of heparan sulfate synthesized by HEK 293 cells overexpressing murine NDST1
and/or NDST2 demonstrated that the amount of heparan sulfate was increased in NDST2 …

Heparan sulfate is a sulfated polysaccharide present on most cell surfaces and in the
extracellular matrix. In vivo functions of heparan sulfate can be studied in mouse strains …

Heparan sulfate (HS) is a highly sulfated polysaccharide participated in essential
physiological functions from regulating cell growth to blood coagulation. HS contains …

Heparin and heparan sulfate are linear sulfated polysaccharides that exert a multitude of
biological functions. Heparan sulfate glucosaminyl N-deacetylase/N-sulfotransferase …

The cDNA and gene encoding human heparan glucosaminyl N-deacetylase/N-
sulphotransferase-2 have been cloned. The cDNA encoded a protein of 883 amino acids …