Role of Serine140 in the mode of action of Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA)
DS Santos, LA Basso, WF de Azevedo, RA Caceres… - 2012 - oa.las.ac.cn
Background Tuberculosis (TB) still remains one of the most deadly infectious diseases in the
world. Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA) is a member of the …
world. Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA) is a member of the …
Role of Serine140 in the mode of action of Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA)
LA Rosado, RA Caceres, WF de Azevedo, LA Basso… - BMC research …, 2012 - Springer
Background Tuberculosis (TB) still remains one of the most deadly infectious diseases in the
world. Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA) is a member of the …
world. Mycobacterium tuberculosis β-ketoacyl-ACP Reductase (MabA) is a member of the …
[PDF][PDF] Phosphorylation of the Mycobacterium tuberculosis ß-Ketoacyl-Acyl Carrier Protein Reductase MabA Regulates Mycolic Acid Biosynthesis
L Kremer - THE JOURNAL OF BIOLOGICAL CHEMISTRY, 2010 - researchgate.net
Mycolic acids are key cell wall components for the survival, pathogenicity, and antibiotic
resistance of the human tubercle bacillus. Although it was thought that Mycobacterium …
resistance of the human tubercle bacillus. Although it was thought that Mycobacterium …
Phosphorylation of the Mycobacterium tuberculosis β-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesis
R Veyron-Churlet, I Zanella-Cléon… - Journal of Biological …, 2010 - ASBMB
Mycolic acids are key cell wall components for the survival, pathogenicity, and antibiotic
resistance of the human tubercle bacillus. Although it was thought that Mycobacterium …
resistance of the human tubercle bacillus. Although it was thought that Mycobacterium …
In Vitro Inhibition of the Mycobacterium tuberculosis β-Ketoacyl-Acyl Carrier Protein Reductase MabA by Isoniazid
S Ducasse-Cabanot, M Cohen-Gonsaud… - Antimicrobial agents …, 2004 - Am Soc Microbiol
The first-line specific antituberculous drug isoniazid inhibits the fatty acid elongation system
(FAS) FAS-II involved in the biosynthesis of mycolic acids, which are major lipids of the …
(FAS) FAS-II involved in the biosynthesis of mycolic acids, which are major lipids of the …
Mycobacterium tuberculosis β-Ketoacyl-Acyl Carrier Protein (ACP) Reductase: Kinetic and Chemical Mechanisms
RG Silva, LPS De Carvalho, JS Blanchard… - Biochemistry, 2006 - ACS Publications
β-ketoacyl-acyl carrier protein (ACP) reductase from Mycobacterium tuberculosis (MabA) is
responsible for the second step of the type-II fatty acid elongation system of bacteria, plants …
responsible for the second step of the type-II fatty acid elongation system of bacteria, plants …
MabA (FabG1), a Mycobacterium tuberculosis protein involved in the long-chain fatty acid elongation system FAS-II
H Marrakchi, S Ducasse, G Labesse… - …, 2002 - microbiologyresearch.org
The fatty acid elongation system FAS-II is involved in the biosynthesis of mycolic acids,
which are very long-chain fatty acids of the cell envelope specific to Mycobacterium …
which are very long-chain fatty acids of the cell envelope specific to Mycobacterium …
Crystal structure of MabA from Mycobacterium tuberculosis, a reductase involved in long-chain fatty acid biosynthesis
M Cohen-Gonsaud, S Ducasse, F Hoh, D Zerbib… - Journal of molecular …, 2002 - Elsevier
The fatty acid elongation system FAS-II is involved in the biosynthesis of mycolic acids,
which are major and specific long-chain fatty acids of the cell envelope of Mycobacterium …
which are major and specific long-chain fatty acids of the cell envelope of Mycobacterium …
Mycobacterium tuberculosis β-ketoacyl-ACP reductase: α-secondary kinetic isotope effects and kinetic and equilibrium mechanisms of substrate binding
RG Silva, LA Rosado, DS Santos, LA Basso - Archives of biochemistry and …, 2008 - Elsevier
β-Ketoacyl-ACP reductase catalyzes the NADPH-dependent reduction of β-ketoacyl-acyl
carrier protein to generate β-hydroxyacyl-acyl carrier protein and NADP+, the second step of …
carrier protein to generate β-hydroxyacyl-acyl carrier protein and NADP+, the second step of …
[引用][C] Phosphorylation of the Mycobacterium tuberculosis β-ketoacyl-ACP reductase MabA regulates mycolic acid biosynthesis
R Veyron-Churlet, I Zanella-Cléon, M Cohen-Gonsaud… - 2010
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