In recent years, several publications reported that nanoparticles larger than the kidney
filtration threshold were found intact in the urine after being injected into laboratory mice …

Kidneys are a major organ for blood filtration and waste elimination and thus play a key role
in the transport and clearance of nanoparticles in vivo. The interactions of nanoparticles with …

The kidneys are vital organs performing several essential functions. Their primary function is
the filtration of blood and the removal of metabolic waste products as well as fluid …

Developing nanocarriers that accumulate in targeted organs and are harmlessly eliminated
still remains a big challenge. Nanoparticles (NP) biodistribution is governed by their size …

Loss and dysfunction of glomerular podocytes result in increased macromolecule
permeability through the glomerular filtration barrier and nephrotic syndrome. Current …

Renal excretion mechanisms, such as glomerular and tubular excretion processes, are an
important part of renal function and provide general information about effective excretion of …

Kidney-targeted nanoparticles have become of recent interest due to their potential to
deliver drugs directly to diseased tissue, decrease off-target adverse effects, and increase …

Inorganic nanoparticle (NP) based imaging contrast agents with tuneable shape, size, and
surface chemistry have immense potential in both basic research and clinical settings …

Through a process of translocation across biological barriers, nanoparticles can reach and
deposit in secondary target organs where they may induce adverse biological reactions …

Nanoparticles possess enormous potential as diagnostic imaging agents and hold promise
for the development of multimodality agents with both imaging and therapeutic capabilities …