Background Lacking protective antibodies, patients with primary antibody deficiencies
(PADs) experience frequent respiratory tract infections, leading to chronic pulmonary …

Bacterial respiratory tract infections are the hallmark of primary antibody deficiencies
(PADs). Because they are also among the most common infections in healthy individuals …

Background Patients with primary antibody deficiency (PAD) are at increased risk of
respiratory tract infections, but our understanding of their nature and consequences remains …

Purpose Pulmonary complications occur frequently in primary antibody deficiency (PAD).
While the impact of antibody deficiency may appear implicit for certain respiratory infections …

Background Viral infection and allergy have been identified as major risk factors for
exacerbation in asthma, especially in the presence of both. However, whether patients with …

Primary antibody deficiencies (PADs) are the most common form of primary
immunodeficiency and predispose to severe and recurrent pulmonary infections, which can …

Long-term prophylactic antibiotics are being widely implemented as primary or adjunctive
therapy in primary immune deficiencies. This practice has transformed clinical outcomes in …

Background Patients with severe asthma are at increased risk of exacerbations and lower
respiratory tract infections (LRTI). Severe asthma is heterogeneous, encompassing …

Defects of antibody production are the most common of the primary immune defects of man.
While these defects have been described in clinical terms for more than five decades, in …

To the Editor, In the majority of primary antibody deficiency (PAD) patients receiving IgG
replacement therapy (IgGRT), the risk of serious infections is reduced; however, a significant …