Background Beta-adrenergic receptor agonists (BA) induce skeletal muscle hypertrophy, yet
specific mechanisms that lead to this effect are not well understood. The objective of this …

β-Adrenergic receptor agonists (BA) stimulate skeletal muscle growth. However,
downstream signaling pathways that facilitate this effect remain poorly defined. Objectives of …

Previously, we highlighted induction of an integrated stress response (ISR) gene program in
skeletal muscle of pigs treated with a beta-adrenergic agonist. Hence we tested the …

Background Systemic administration of β-adrenoceptor (β-AR) agonists has been found to
induce skeletal muscle hypertrophy and significant metabolic changes. In the context of …

Certain β2‐adrenoceptor agonists, such as clenbuterol, are known to elicit a muscle‐specific
anabolism or hypertrophy in both normal and catabolic muscle in a wide variety of species …

The molecular mechanisms controlling β-adrenergic receptor agonist (BA)-induced skeletal
muscle hypertrophy are not well known. We presently report that BA exerts a distinct muscle …

Muscle wasting affects large numbers of people, but few therapeutic approaches exist to
treat and/or reverse this condition. The β2-adrenoceptor agonist clenbuterol produces a …

Chronic administration of clenbuterol (CB), a lipophilic b2-adrenoceptor (b2-AR) agonist,
induces skeletal muscle hypertrophy and slow-to-fast fiber–type transitions in mammalian …

The β2-agonist clenbuterol [4-amino-α (t-butyl-amino) methyl-3, 5-dichlorobenzyl alcohol] is
used as a non-steroidal anabolic drug for sports doping. The effects of clenbuterol on the …

Background Beta-2 agonists are widely used in the treatment of asthma and chronic
obstructive pulmonary disease for their effect on airway smooth muscle relaxation. They also …