Identification of starvation-mimetic bioactive phytocomponent from Withania somnifera using in-silico molecular modelling and flow cytometry-based analysis for the …
D Pradhan, P Biswasroy, S Kulkarni… - Journal of …, 2024 - Taylor & Francis
Multidrug resistance episodes in malaria increased from 3.9% to 20% from 2015 to 2019.
Synchronizing the clinical manifestation in chronological sequence led to a unique …
Synchronizing the clinical manifestation in chronological sequence led to a unique …
Isolation and structure elucidation of a steroidal moiety from Withania somnifera and in silico evaluation of antimalarial efficacy against artemisinin resistance …
According to the 2021 Malaria report, 241 million clinical episodes with 627000 deaths
penalty was estimated across the worldwide. However, mutation in the propeller domain of …
penalty was estimated across the worldwide. However, mutation in the propeller domain of …
In silico modeling revealed phytomolecules derived from Cymbopogon citratus (DC.) leaf extract as promising candidates for malaria therapy
IO Evbuomwan, OO Alejolowo, TC Elebiyo… - Journal of …, 2024 - Taylor & Francis
The emergence of varying levels of resistance to currently available antimalarial drugs
significantly threatens global health. This factor heightens the urgency to explore bioactive …
significantly threatens global health. This factor heightens the urgency to explore bioactive …
Antimalarial potential, LC–MS secondary metabolite profiling and computational studies of Zingiber officinale
KO Faloye, MK Tripathi, SA Adesida… - Journal of …, 2024 - Taylor & Francis
Malaria is among the top-ranked parasitic diseases that pose a threat to the existence of the
human race. This study evaluated the antimalarial effect of the rhizome of Zingiber officinale …
human race. This study evaluated the antimalarial effect of the rhizome of Zingiber officinale …
Modulation of GPCR receptors common to gut inflammatory diseases and neuronal disorders, Alzheimer's and Parkinson's diseases as druggable targets through …
Microorganisms in human gastrointestinal tract have profound influence on the
transformation of food into metabolites which can impact human health. Along with playing …
transformation of food into metabolites which can impact human health. Along with playing …
Bioactivity-guided isolation of antiplasmodial constituents from Conyza sumatrensis (Retz.) EH Walker
PK Boniface, S Verma, A Shukla, HS Cheema… - Parasitology …, 2015 - Elsevier
Abstract Conyza sumatrensis (Retz.) EH Walker (Cs) leaves are used for traditional
treatment of malaria in Cameroon. However, the antimalarial activity of the leaf constituents …
treatment of malaria in Cameroon. However, the antimalarial activity of the leaf constituents …
[PDF][PDF] A Docking Study on Various Secondary Metabolites from W. somnifera on Tetrahydrodipicolinate N-Succinyltransferase Protein Involved in The Lysine …
AK Nagwani, D Kashya - Mol Bio, 2018 - researchgate.net
A crucial survival factor for leading pathogen (carrying 40-60% mortality rate) is
Tetrahydrodipicolinate N-Succinyltransferase (DAPD EC 2.3. 1.117) involves in lysine …
Tetrahydrodipicolinate N-Succinyltransferase (DAPD EC 2.3. 1.117) involves in lysine …
In-silico validation of novel therapeutic activities of withaferin a using molecular docking and dynamics studies
R Surya Ulhas, A Malaviya - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Withaferin A is a bioactive molecule of W. somnifera. We access its efficacy against various
target proteins associated with Cancer, Type-II Diabetes and hypercholesterolemia using …
target proteins associated with Cancer, Type-II Diabetes and hypercholesterolemia using …
A computational approach to validate novel drug targets of gentianine from Swertiya chirayita in Plasmodium falciparum
RK Mahapatra, M Das - Biosystems, 2020 - Elsevier
Gentianine is one of the compounds found in the plant Swertiya chirayita that is known for its
antimalarial activity. However, its exact molecular mechanism of action is yet to be …
antimalarial activity. However, its exact molecular mechanism of action is yet to be …
Estimation of drug-likeness properties of GC–MS separated bioactive compounds in rare medicinal Pleione maculata using molecular docking technique and …
HD Sympli - Network Modeling Analysis in Health Informatics and …, 2021 - Springer
The main aim of the paper was to determine bioactive compounds in Pleione maculata
extracts using gas chromatographic technique and to investigate their drug-likeness …
extracts using gas chromatographic technique and to investigate their drug-likeness …
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