Metrics of sleep apnea severity: beyond the apnea-hypopnea index

A Malhotra, I Ayappa, N Ayas, N Collop, D Kirsch… - Sleep, 2021 - academic.oup.com
Obstructive sleep apnea (OSA) is thought to affect almost 1 billion people worldwide. OSA
has well established cardiovascular and neurocognitive sequelae, although the optimal …

Untreated obstructive sleep apnea and the risk for serious long-term adverse outcomes: a systematic review

T Kendzerska, T Mollayeva, AS Gershon… - Sleep medicine …, 2014 - Elsevier
Background Reports on the association between obstructive sleep apnea (OSA) and risk of
death, cardiovascular (CV) events, diabetes and depression have been inconsistent …

The Sleep Revolution project: the concept and objectives

ES Arnardottir, AS Islind, M Óskarsdottir… - Journal of sleep …, 2022 - Wiley Online Library
Obstructive sleep apnea is linked to severe health consequences such as hypertension,
daytime sleepiness, and cardiovascular disease. Nearly a billion people are estimated to …

More than the sum of the respiratory events: personalized medicine approaches for obstructive sleep apnea

BA Edwards, S Redline, SA Sands… - American journal of …, 2019 - atsjournals.org
Traditionally, the presence and severity of obstructive sleep apnea (OSA) have been defined
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …

Phenotypes in obstructive sleep apnea: a definition, examples and evolution of approaches

AV Zinchuk, MJ Gentry, J Concato, HK Yaggi - Sleep medicine reviews, 2017 - Elsevier
Obstructive sleep apnea (OSA) is a complex and heterogeneous disorder and the apnea
hypopnea index alone can not capture the diverse spectrum of the condition. Enhanced …

[HTML][HTML] Diagnosis and treatment of obstructive sleep apnea in adults

EM Balk, D Moorthy, NO Obadan, K Patel, S Ip… - 2011 - europepmc.org
Background Methods for diagnosing and treating obstructive sleep apnea (OSA) are
cumbersome, resource-intensive, and often inconvenient for the patient. Purpose …

[HTML][HTML] Obstructive sleep apnea with or without excessive daytime sleepiness: clinical and experimental data-driven phenotyping

S Garbarino, E Scoditti, P Lanteri, L Conte… - Frontiers in …, 2018 - frontiersin.org
Introduction: Obstructive sleep apnea (OSA) is a serious and prevalent medical condition
with major consequences for health and safety. Excessive daytime sleepiness (EDS) is a …

A novel model to estimate key obstructive sleep apnea endotypes from standard polysomnography and clinical data and their contribution to obstructive sleep apnea …

R Dutta, G Delaney, B Toson, AS Jordan… - Annals of the …, 2021 - atsjournals.org
Rationale: There are at least four key pathophysiological endotypes that contribute to
obstructive sleep apnea (OSA) pathophysiology. These include 1) upper-airway …

Validation of the STOP-Bang questionnaire as a screening tool for obstructive sleep apnea among different populations: a systematic review and meta-analysis

M Nagappa, P Liao, J Wong, D Auckley… - PloS one, 2015 - journals.plos.org
Background Diagnosing obstructive sleep apnea (OSA) is clinically relevant because
untreated OSA has been associated with increased morbidity and mortality. The STOP-Bang …

Obstructive sleep apnea screening with a 4-item instrument, named GOAL questionnaire: development, validation and comparative study with No-Apnea, STOP-Bang …

RLM Duarte, FJ Magalhães-da-Silveira… - Nature and Science …, 2020 - Taylor & Francis
Background Obstructive sleep apnea (OSA) is a very prevalent disorder. Here, we aimed to
develop and validate a practical questionnaire with yes-or-no answers, and to compare its …