[PDF][PDF] Transcriptome Dysregulation in Hepatoblastoma: The Pivotal Role of Noncoding Rnas and Changes in Lipid Metabolism
MP Rivas, TFM Aguiar, EM de Andrade, SF Pires… - 2022 - researchgate.net
Hepatoblastoma, the most common liver tumor in children and exhibited the lowest
mutational burden among solid cancers, pointing to chromosomal and epigenetic changes …
mutational burden among solid cancers, pointing to chromosomal and epigenetic changes …
First Transcriptome Analysis of Hepatoblastoma in Brazil: Unraveling the Pivotal Role of Noncoding RNAs and Metabolic Pathways
TFM Aguiar, MP Rivas, EM de Andrade Silva… - Biochemical …, 2024 - Springer
Hepatoblastoma stands as the most prevalent liver cancer in the pediatric population.
Characterized by a low mutational burden, chromosomal and epigenetic alterations are key …
Characterized by a low mutational burden, chromosomal and epigenetic alterations are key …
Whole-genome sequencing and RNA sequencing analysis reveals novel risk genes and differential expression patterns in hepatoblastoma
W Wang, N Zhang, L Chen, X Zhao, Y Shan, F Yang… - Gene, 2024 - Elsevier
Hepatoblastoma (HB) is an uncommon malignant liver cancer primarily affecting infants and
children, characterized by the presence of tissue that resembling fetal hepatocytes, mature …
children, characterized by the presence of tissue that resembling fetal hepatocytes, mature …
Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications
J Carrillo-Reixach, L Torrens, M Simon-Coma… - Journal of …, 2020 - Elsevier
Background & Aims Hepatoblastoma (HB) is a rare disease. Nevertheless, it is the
predominant pediatric liver cancer, with limited therapeutic options for patients with …
predominant pediatric liver cancer, with limited therapeutic options for patients with …
Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets
Although hepatoblastoma is the most common pediatric liver cancer, its genetic
heterogeneity and therapeutic targets are not well elucidated. Therefore, we conducted a …
heterogeneity and therapeutic targets are not well elucidated. Therefore, we conducted a …
[HTML][HTML] Identification of differentially expressed genes, lncRNAs and miRNAs which are associated with tumor malignant phenotypes in hepatoblastoma patients
S Liu, F Xie, X Xiang, S Liu, S Dong, K Qu, T Lin - Oncotarget, 2017 - ncbi.nlm.nih.gov
Hepatoblastoma (HB) is one of the most common hepatic malignancies in the pediatric
population. HB are composed of a variety of tumors, which derived from different origins and …
population. HB are composed of a variety of tumors, which derived from different origins and …
[HTML][HTML] Mutational signature, cancer driver genes mutations and transcriptomic subgroups predict hepatoblastoma survival
Background Hepatoblastoma is the most frequent pediatric liver cancer. The current
treatments lead to 80% of survival rate at 5 years. In this study, we evaluated the clinical …
treatments lead to 80% of survival rate at 5 years. In this study, we evaluated the clinical …
The genomic landscape of hepatoblastoma and their progenies with HCC-like features
M Eichenmüller, F Trippel, M Kreuder, A Beck… - Journal of …, 2014 - Elsevier
Background & Aims Hepatoblastoma (HB) is the most common childhood liver cancer and
occasionally presents with histological and clinical features reminiscent of hepatocellular …
occasionally presents with histological and clinical features reminiscent of hepatocellular …
[PDF][PDF] Bridging molecular basis, prognosis, and treatment of pediatric liver tumors
C Armengol, S Cairo, R Kappler - Hepatoma Res, 2021 - f.oaes.cc
A deeper understanding of the genetic and molecular basis of hepatoblastoma (HB) has
fueled the hope to help in identifying genes and signaling pathways that are amenable to …
fueled the hope to help in identifying genes and signaling pathways that are amenable to …
The role of microRNAs in hepatoblastoma tumors
I Cristóbal, M Sanz-Álvarez, M Luque, C Caramés… - Cancers, 2019 - mdpi.com
Hepatoblastoma is the most common hepatic malignancy during childhood. However, little is
still known about the molecular mechanisms that govern the development of this disease …
still known about the molecular mechanisms that govern the development of this disease …