Recent developments on the synthesis of biologically active glycohybrids
The exploration of hybridization emerges as a potent tool in advancing drug discovery
research, with a significant emphasis on carbohydrate-containing hybrid scaffolds. Evidence …
research, with a significant emphasis on carbohydrate-containing hybrid scaffolds. Evidence …
Recent progress in the synthesis of natural product inspired bioactive glycohybrids
Carbohydrates are a basic structural component that are indispensable to all cellular
processes. In addition to being employed as chiral starting materials in the synthesis of a …
processes. In addition to being employed as chiral starting materials in the synthesis of a …
[HTML][HTML] Recent advances in the synthesis of bioactive glycohybrids via click-chemistry
Carbohydrates, traditionally known for their energy-providing role, have gained significant
attention in drug discovery due to their diverse bioactivities and stereodiversity. However …
attention in drug discovery due to their diverse bioactivities and stereodiversity. However …
Carbohydrates in diversity-oriented synthesis: challenges and opportunities
E Lenci, G Menchi, A Trabocchi - Organic & Biomolecular Chemistry, 2016 - pubs.rsc.org
Over the last decade, Diversity-Oriented Synthesis (DOS) has become a new paradigm for
developing large collections of structurally diverse small molecules as probes to investigate …
developing large collections of structurally diverse small molecules as probes to investigate …
Development of Diverse Range of Biologically Relevant Carbohydrate‐Containing Molecules: Twenty Years of Our Journey
VK Tiwari - The Chemical Record, 2021 - Wiley Online Library
There is an increasing demand for significant amount of carbohydrate‐containing molecules
owing to their complete chemical, biological, and pharmacological investigations to better …
owing to their complete chemical, biological, and pharmacological investigations to better …
Recent trends and challenges on carbohydrate-based molecular scaffolding: General consideration toward impact of carbohydrates in drug discovery and …
N Mishra, VK Tiwari, RR Schmidt - Carbohydrates in Drug Discovery and …, 2020 - Elsevier
Carbohydrates, the structural building blocks of genetic materials and vital source of energy,
are integral part of the living cells as they play important roles in biological system …
are integral part of the living cells as they play important roles in biological system …
Carbohydrate-based therapeutics: a frontier in drug discovery and development
S Mishra, K Upadhaya, KB Mishra, AK Shukla… - Studies in Natural …, 2016 - Elsevier
Carbohydrates, one of the most abundant classes of biomolecules, are the structural
building blocks of genetic materials and vital source of energy. They are integral part of the …
building blocks of genetic materials and vital source of energy. They are integral part of the …
Carbohydrate mimetics and scaffolds: sweet spots in medicinal chemistry
Several glycoprocessing enzymes and glycoreceptors have been recognized as important
targets for therapeutic intervention. This concept has inspired the development of important …
targets for therapeutic intervention. This concept has inspired the development of important …
Glycohybrid molecules in medicinal chemistry: Present status and future prospective
Hybrid molecules combine two distinct biologically relevant molecules that act at different
biological targets with new mechanism are becoming molecules for interest among …
biological targets with new mechanism are becoming molecules for interest among …
Recent developments in solid-and solution-phase methods for generating carbohydrate libraries.
MJ Sofia, DJ Silva - Current Opinion in Drug Discovery & …, 1999 - europepmc.org
Carbohydrates and glycoconjugates have attracted a great deal of attention in recent years
because of the key roles they play in biological processes. The development of …
because of the key roles they play in biological processes. The development of …