Acquired sensorineural hearing loss is one of the most prevalent chronic diseases, and
aging and acoustic overexposure are common contributors. Decades of study in animals …

Noise-induced hearing loss (NIHL) is a common injury for service members and civilians.
Effective prevention of NIHL with drug agents would reduce the prevalence of NIHL. There …

Introduction Excessive exposure to noise is a common occurrence that contributes to
approximately 50% of the non-genetic hearing loss cases. Researchers need to develop …

Once an oddity, mice have become the most widely used hearing research model. Their
value for research in noise-induced hearing loss (NIHL) stems from their high vulnerability to …

Age-related hearing loss is a very common sensory disability, affecting one in three older
adults. Establishing a link between anatomical, physiological, and behavioral markers of …

Understanding underlying pathological mechanisms is prerequisite for a sensible design of
protective therapies against hearing loss. The triad of age-related, noise-generated, and …

The classic view of sensorineural hearing loss has been that the primary damage targets are
hair cells and that auditory nerve loss is typically secondary to hair cell degeneration …

There is a huge potential market for the treatment of hearing loss. Drugs are already
available to ameliorate predictable, damaging effects of excessive noise and ototoxic drugs …

Sensorineural hearing loss (SNHL) affects approximately 466 million people worldwide,
which is projected to reach 900 million by 2050. Its histological characteristics are lesions in …

Age-related and noise-induced hearing losses in humans are multifactorial, with
contributions from, and potential interactions among, numerous variables that can shape …