Liver fibrosis is a common chronic hepatic disease. This study was done to examine the
effect of pyridoxamine against thioacetamide-induced hepatic fibrosis. Animals were divided …

Background and objective: Liver fibrosis is a major health problem. Till now, no successful
treatment developed for this liver disorder. This experimental study aimed to assess effects …

Aims Naringin (NR) is a flavanone glycoside extracted from grapefruits and citrus fruits. The
aim of this study is to investigate the antifibrotic efficacy of NR in thioacetamide (TAA) …

Aims Liver fibrosis (LF) is a life-threatening complication of most chronic liver diseases
resulting from a variety of injurious agents and hepatotoxic insults. To date, there are no …

Liver fibrosis is a health concern that leads to organ failure mediated via production of
inflammatory cytokines and fibrotic biomarkers. This study aimed to explore the protective …

Background: Many therapeutic strategies have been proposed to treat liver fibrosis, but no
drugs have been proved effective. Matrix metalloproteinases (MMPs) have been reported to …

In liver fibrosis, conversion of fibroblasts to profibrogenic myofibroblasts significantly drives
the development of the disease. A crucial role of cyclic adenosine monophosphate (cAMP) …

Piceatannol is a polyphenolic analog of resveratrol that selectively inhibits the non-receptor
tyrosine kinase-Syk. This study investigates the potential ability of piceatannol to attenuate …

Abstract L-2-Oxothiazolidine-4-carboxylic acid (OTC) is a cysteine prodrug that maintains
glutathione in tissues. The present study was designed to investigate anti-fibrotic and anti …

BACKGROUND AND AIM: Oxidative stress contributes to liver fibrosis through the activation
of hepatic stellate cells. In a cell-based screening study, a class of imidazolium salts …