Unveiling the connection: long-chain non-coding RNAs and critical signaling pathways in breast cancer

R Thapa, O Afzal, G Gupta, AA Bhat, WH Almalki… - … -Research and Practice, 2023 - Elsevier
Breast cancer is a complex and diverse condition that disrupts multiple signaling pathways
essential for cell proliferation, survival, and differentiation. Recently, the significant …

[HTML][HTML] Dysregulation of long non-coding RNA in breast cancer: an overview of mechanism and clinical implication

J Wang, C Ye, H Xiong, Y Shen, Y Lu, J Zhou… - Oncotarget, 2016 - pmc.ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs), which occupy nearly 98% of genome, have crucial roles
in cancer development, including breast cancer. Breast cancer is a disease with high …

[HTML][HTML] lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment

H Jin, W Du, W Huang, J Yan, Q Tang, Y Chen… - … Therapy-Nucleic Acids, 2021 - cell.com
Breast cancer is a malignant tumor that has a high mortality rate and mostly occurs in
women. Although significant progress has been made in the implementation of personalized …

A brief review on long noncoding RNAs: a new paradigm in breast cancer pathogenesis, diagnosis and therapy

S Malih, M Saidijam, N Malih - Tumor Biology, 2016 - Springer
With the development of technologies such as microarrays and RNA deep sequencing, long
noncoding RNAs (lncRNAs) have become the focus of cancer investigations. LncRNAs …

Critical roles of long noncoding RNAs in breast cancer

M Abolghasemi, SS Tehrani, T Yousefi… - Journal of cellular …, 2020 - Wiley Online Library
Breast cancer is a major clinical challenge that affects a wide range of the female population
and heavily burdens the health system. In the past few decades, attempts have been made …

[HTML][HTML] Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes

X Su, GG Malouf, Y Chen, J Zhang, H Yao, V Valero… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Accumulating evidence highlights the potential role of long non-coding RNAs (lncRNAs) as
biomarkers and therapeutic targets in solid tumors. However, the role of lncRNA expression …

Emerging roles of long non-coding RNAs in breast cancer biology and management

I Amelio, F Bernassola, E Candi - Seminars in cancer biology, 2021 - Elsevier
Breast cancer is the most common cancer in women with the highest mortality among this
gender. Despite treatment strategies including surgery, hormone therapy and targeted …

Oncogenic long noncoding RNA landscape in breast cancer

S Xu, D Kong, Q Chen, Y Ping, D Pang - Molecular cancer, 2017 - Springer
Abstract Background Few long noncoding RNAs (lncRNAs) that act as oncogenic genes in
breast cancer have been identified. Methods Oncogenic lncRNAs associated with …

Portraying breast cancers with long noncoding RNAs

O Van Grembergen, M Bizet, EJ de Bony… - Science …, 2016 - science.org
Evidence is emerging that long noncoding RNAs (lncRNAs) may play a role in cancer
development, but this role is not yet clear. We performed a genome-wide transcriptional …

LncRNAs in breast cancer: a link to future approaches

N Sideris, P Dama, S Bayraktar, T Stiff… - Cancer gene …, 2022 - nature.com
Breast cancer affects millions of women each year. Despite recent advances in targeted
treatments breast cancer remains a significant threat to women's health. In recent years the …