Anti-islet autoantibodies serve as key markers in immune-mediated type 1 diabetes (T1D)
and slowly progressive T1D (SPIDDM), also known as latent autoimmune diabetes in adults …

Type 1 diabetes mellitus (T1D) is an autoimmune disease encompassing the T-cell-
mediated destruction of pancreatic β cells and the production of autoantibodies against islet …

Type 1 diabetes mellitus (T1DM) has been shown to be a disease characterized by immune-
mediated destruction of the insulin-producing islet beta-cells (β-cells) in the pancreas …

Abstract Type 1 diabetes (T1D) is an autoimmune disease characterized by loss of insulin
producing beta cells and reliance on exogenous insulin for survival. T1D is one of the most …

The presence of islet autoantibodies remains a reliable biomarker to identify individuals at
high risk of developing type 1 diabetes. As such, these autoantibodies play a pivotal role in …

Islet autoantibodies are the main markers of pancreatic autoimmunity in type 1 diabetes
(T1D). Islet autoantibodies recognize insulin (IAA), glutamic acid decarboxylase (GADA) …

Type 1 diabetes mellitus (T1DM), also known as autoimmune diabetes, is a chronic disease
characterized by insulin deficiency due to pancreatic β-cell loss and leads to …

Abstract Immune‐mediated (auto‐immune) Type 1 diabetes mellitus is not a homogenous
entity, but nonetheless has distinctive characteristics. In children, it may present with …

Autoantibodies against Glutamic Acid Decarboxylase (GADA), insulinoma antigen-2 (IA-2A),
insulin (IAA) and the most recently Zinc Transporter 8 (ZnT8A) are one of the most reliable …

Type 1 diabetes mellitus (T1DM) is characterized by recognition of beta cell proteins as self-
antigens, called autoantigens (AAgs), by patients' own CD4+ and CD8+ T cells and/or the …