Asymmetric Histone Inheritance: Establishment, Recognition, and Execution
The discovery of biased histone inheritance in asymmetrically dividing Drosophila
melanogaster male germline stem cells demonstrates one means to produce two distinct …
melanogaster male germline stem cells demonstrates one means to produce two distinct …
Asymmetric distribution of histones during Drosophila male germline stem cell asymmetric divisions
It has long been known that epigenetic changes are inheritable. However, except for DNA
methylation, little is known about the molecular mechanisms of epigenetic inheritance. Many …
methylation, little is known about the molecular mechanisms of epigenetic inheritance. Many …
Asymmetric histone inheritance in asymmetrically dividing stem cells
Epigenetic mechanisms play essential roles in determining distinct cell fates during the
development of multicellular organisms. Histone proteins represent crucial epigenetic …
development of multicellular organisms. Histone proteins represent crucial epigenetic …
Mitotic drive in asymmetric epigenetic inheritance
Asymmetric cell division (ACD) produces two daughter cells with distinct cell fates. This
division mode is widely used during development and by adult stem cells during tissue …
division mode is widely used during development and by adult stem cells during tissue …
Symmetry from asymmetry or asymmetry from symmetry?
EW Kahney, R Ranjan, RJ Gleason… - Cold Spring Harbor …, 2017 - symposium.cshlp.org
The processes of DNA replication and mitosis allow the genetic information of a cell to be
copied and transferred reliably to its daughter cells. However, if DNA replication and cell …
copied and transferred reliably to its daughter cells. However, if DNA replication and cell …
Differential condensation of sister chromatids acts with Cdc6 to ensure asynchronous S-phase entry in Drosophila male germline stem cell lineage
During Drosophila melanogaster male germline stem cell (GSC) asymmetric division,
preexisting old versus newly synthesized histones H3 and H4 are asymmetrically inherited …
preexisting old versus newly synthesized histones H3 and H4 are asymmetrically inherited …
Characterization of histone inheritance patterns in the Drosophila female germline
EW Kahney, EH Zion, L Sohn, K Viets‐Layng… - EMBO …, 2021 - embopress.org
Stem cells have the unique ability to undergo asymmetric division which produces two
daughter cells that are genetically identical, but commit to different cell fates. The loss of this …
daughter cells that are genetically identical, but commit to different cell fates. The loss of this …
Asymmetric centromeres differentially coordinate with mitotic machinery to ensure biased sister chromatid segregation in germline stem cells
Many stem cells utilize asymmetric cell division (ACD) to produce a self-renewed stem cell
and a differentiating daughter cell. How non-genic information could be inherited …
and a differentiating daughter cell. How non-genic information could be inherited …
A single N-terminal amino acid determines the distinct roles of histones H3 and H3.3 in the Drosophila male germline stem cell lineage
C Chandrasekhara, R Ranjan, JA Urban… - Plos …, 2023 - journals.plos.org
Adult stem cells undergo asymmetric cell divisions to produce 2 daughter cells with distinct
cell fates: one capable of self-renewal and the other committed for differentiation …
cell fates: one capable of self-renewal and the other committed for differentiation …
Centromere function in asymmetric cell division in Drosophila female and male germline stem cells
AM Kochendoerfer, F Modafferi… - Open …, 2021 - royalsocietypublishing.org
The centromere is the constricted chromosomal region required for the correct separation of
the genetic material at cell division. The kinetochore protein complex assembles at the …
the genetic material at cell division. The kinetochore protein complex assembles at the …