Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐and aging‐related diseases

AG Panossian, T Efferth, AN Shikov… - Medicinal research …, 2021 - Wiley Online Library
Adaptogens comprise a category of herbal medicinal and nutritional products promoting
adaptability, resilience, and survival of living organisms in stress. The aim of this review was …

Understanding adaptogenic activity: specificity of the pharmacological action of adaptogens and other phytochemicals

A Panossian - Annals of the New York Academy of Sciences, 2017 - Wiley Online Library
Adaptogens are stress‐response modifiers that increase an organism's nonspecific
resistance to stress by increasing its ability to adapt and survive. The classical reductionist …

[HTML][HTML] Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology

A Panossian, EJ Seo, T Efferth - Phytomedicine, 2018 - Elsevier
Introduction Adaptogens are natural compounds or plant extracts that increase adaptability
and survival of organisms under stress. Adaptogens stimulate cellular and organismal …

[图书][B] Adaptogens: herbs for strength, stamina, and stress relief

D Winston - 2019 - books.google.com
An updated and expanded edition of the definitive guide to adaptogenic herbs• Includes a
Materia Medica with monographs covering 25 adaptogens, including eleuthero, ginseng …

A literature review of the studies concerning selected plant-derived adaptogens and their general function in body with a focus on animal studies

N Esmaealzadeh, A Iranpanah, J Sarris, R Rahimi - Phytomedicine, 2022 - Elsevier
Background Adaptogens are generally referred to the substances, mostly found in plants,
which non-specifically increase resilience and chances of survival by activation of signaling …

Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity

A Panossian, G Wikman - Current clinical pharmacology, 2009 - ingentaconnect.com
The aim of this review article is to assess the level of scientific evidence presented by clinical
trials of adaptogens in fatigue, and to provide a rationale at the molecular level for verified …

The role of adaptogens in stress management

R Provino - Australian Journal of Medical Herbalism, 2010 - search.informit.org
Stress is a normal part of everyday life but it is important to be able to use tools for its
management otherwise chronic stress, if left untreated, can lead to a variety of stress related …

A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide

L Liao, Y He, L Li, H Meng, Y Dong, F Yi, P Xiao - Chinese medicine, 2018 - Springer
Modern studies have shown that adaptogens can non-specifically enhance the resistance of
human body under a wide range of external stress conditions with a multi-targeted and multi …

Plant adaptogens—History and future perspectives

V Todorova, K Ivanov, C Delattre, V Nalbantova… - Nutrients, 2021 - mdpi.com
Adaptogens are synthetic compounds (bromantane, levamisole, aphobazole, bemethyl, etc.)
or plant extracts that have the ability to enhance the body's stability against physical loads …

[PDF][PDF] Adaptogens in mental and behavioral disorders

AG Panossian - Psychiatric Clinics, 2013 - researchgate.net
The term adaptogen was introduced into scientific literature in 1958 to denote substances
that increase the “state of nonspecific resistance” during stress, based on Hans Selye's …