[HTML][HTML] Anxiolytic, Promnesic, Anti-Acetylcholinesterase and Antioxidant Effects of Cotinine and 6-Hydroxy-L-Nicotine in Scopolamine-Induced Zebrafish (Danio rerio …

RS Boiangiu, M Mihasan, DL Gorgan, BA Stache… - Antioxidants, 2021 - mdpi.com
Cotinine (COT) and 6-hydroxy-L-nicotine (6HLN) are two nicotinic derivatives that possess
cognitive-improving abilities and antioxidant properties in different rodent models of …

[HTML][HTML] Cotinine and 6-Hydroxy-L-Nicotine Reverses Memory Deficits and Reduces Oxidative Stress in Aβ25-35-Induced Rat Model of Alzheimer's Disease

RS Boiangiu, M Mihasan, DL Gorgan, BA Stache… - Antioxidants, 2020 - mdpi.com
The nicotinic derivatives, cotinine (COT), and 6-hydroxy-L-nicotine (6HLN), showed
promising cognitive-improving effects without exhibiting the nicotine's side-effects. Here, we …

[HTML][HTML] Rosmarinus officinalis Essential Oil Improves Scopolamine-Induced Neurobehavioral Changes via Restoration of Cholinergic Function and Brain Antioxidant Status in …

L Capatina, RS Boiangiu, G Dumitru, EM Napoli… - Antioxidants, 2020 - mdpi.com
Rosmarinus officinalis L. is a traditional herb with various therapeutic applications such as
antibacterial, antioxidant, anti-inflammatory, antidepressant, and anticholinesterase …

Enhanced behavioral response by decreasing brain oxidative stress to 6-hydroxy-l-nicotine in Alzheimer's disease rat model

L Hritcu, M Stefan, R Brandsch, M Mihasan - Neuroscience Letters, 2015 - Elsevier
Hydroxy-l-nicotine (6HLN) is a nicotine metabolite resulted from nicotine degradation within
Arthrobacter nicotinovorans with positive effects on spatial memory and oxidative stress …

[HTML][HTML] Ameliorative Effects of Rhoifolin in Scopolamine-Induced Amnesic Zebrafish (Danio rerio) Model

I Brinza, AM Abd-Alkhalek, MA El-Raey, RS Boiangiu… - Antioxidants, 2020 - mdpi.com
Rhoifolin (Rho) exerts many biological activities such as anticancer, antidiabetic,
hepatoprotective, antirheumatic, antibacterial, and antiviral properties. The neuroprotective …

Nicotine versus 6-hydroxy-l-nicotine against chlorisondamine induced memory impairment and oxidative stress in the rat hippocampus

L Hritcu, R Ionita, DE Motei, C Babii, M Stefan… - Biomedicine & …, 2017 - Elsevier
Hydroxy-l-nicotine (6HLN), a nicotine derivative from nicotine degradation by Arthrobacter
nicotinovorans pAO1 strain was found to improve behavioral deficits and to reverse …

[HTML][HTML] AD− 1 small molecule improves learning and memory function in scopolamine-induced amnesic mice model through regulation of CREB/BDNF and NF-κB …

R Balakrishnan, JY Park, DY Cho, JY Ahn, DS Yoo… - Antioxidants, 2023 - mdpi.com
Cognitive decline and memory impairment induced by oxidative brain damage are the
critical pathological hallmarks of Alzheimer's disease (AD). Based on the potential …

[HTML][HTML] Direct Evidence for Using Coriandrum sativum var. microcarpum Essential Oil to Ameliorate Scopolamine-Induced Memory Impairment and Brain Oxidative …

I Brinza, RS Boiangiu, O Cioanca, M Hancianu… - Antioxidants, 2023 - mdpi.com
Essential oil from Coriandrum sativum has been demonstrated to provide various
pharmacological properties, such as antioxidant, antimicrobial, antibacterial, antifungal …

[HTML][HTML] Bay Leaf (Laurus Nobilis L.) Incense Improved Scopolamine-Induced Amnesic Rats by Restoring Cholinergic Dysfunction and Brain Antioxidant Status

I Brinza, RS Boiangiu, M Hancianu, O Cioanca… - Antioxidants, 2021 - mdpi.com
Bay leaf (Laurus nobilis L.) has been shown to possesses various biological activities such
as wound healing activity, antioxidant activity, antibacterial activity, antiviral activity …

[HTML][HTML] Thymus vulgaris Essential Oil Protects Zebrafish against Cognitive Dysfunction by Regulating Cholinergic and Antioxidants Systems

L Capatina, E Todirascu-Ciornea, EM Napoli… - Antioxidants, 2020 - mdpi.com
Thymus vulgaris L. is an aromatic herb used for medicinal purposes such as antimicrobial,
spasmolytic, antioxidant, anti-inflammatory, antinociceptive, antitumor, and may have …