Gefitinib is an effective treatment for patients with locally advanced non-small cell lung
cancer. However, it is associated with cardiotoxicity that can limit its clinical use. Liraglutide …

Doxorubicin (Dox)-induced cardiotoxicity constitutes the major adverse effect that limited its
use. We investigated the possible protective effects of liraglutide on Dox-induced …

Necroptosis is a crucial programmed cell death that is tightly associated with myocardial
ischemia/reperfusion injury (MI/RI). Liraglutide is an effective option for the treatment of type …

Doxorubicin is an effective drug for cancer treatment; however, cardiotoxicity limits its use.
Cardiotoxicity pathophysiology is multifactorial. GLP-1 analogues have been shown to …

Objective: Hyperglycemia-mediated cardiomyocyte damage is associated with inflammation
and AMPK inactivation. Aim: The aim of our study is to explore the protective effects exerted …

Liraglutide (LIRA), a drug used to treat type 2 diabetes mellitus that belongs to the glucagon-
like peptide-1 class, has recently drawn attention for its potential cardioprotective properties …

Objective (s): Liraglutide, a well-established drug for treating diabetes mellitus (DM), has
recently gained attention for its cardiovascular benefits in diabetes via multiple cellular …

Cardiac inflammation plays a critical role in the development of heart failure. Inflammation-
induced oxidative stress contributes to aberrant cardiac metabolism and mitochondrial …

OBJECTIVE: Methotrexate (MTX) is one of the most commonly used anti-cancer drugs for
various types of neoplasms. It is associated with multiple cytotoxic effects including …

Purpose This study aimed to investigate whether inhibition of glucagon-like peptide-1 (GLP-
1) on pressure overload induced cardiac hypertrophy and apoptosis is related to activation …