[HTML][HTML] How RNA-binding proteins interact with RNA: molecules and mechanisms

M Corley, MC Burns, GW Yeo - Molecular cell, 2020 - cell.com
RNA-binding proteins (RBPs) comprise a large class of over 2,000 proteins that interact with
transcripts in all manner of RNA-driven processes. The structures and mechanisms that …

High-throughput characterization of protein–RNA interactions

KB Cook, TR Hughes, QD Morris - Briefings in functional …, 2015 - academic.oup.com
RNA-binding proteins (RBPs) are important regulators of eukaryotic gene expression.
Genomes typically encode dozens to hundreds of proteins containing RNA-binding …

RNA–protein interactions

KB Hall - Current opinion in structural biology, 2002 - Elsevier
Recent discoveries have revealed that there is a myriad of RNAs and associated RNA-
binding proteins that spatially and temporally appear in the cells of all organisms. The …

Determinants of affinity and specificity in RNA-binding proteins

S Helder, AJ Blythe, CS Bond, JP Mackay - Current opinion in structural …, 2016 - Elsevier
Highlights•Interactions between RNA and RNA-binding proteins (RBPs) are typified by
diversity.•Many enigmatic RBPs have been reported, but their interactions are poorly …

Methods to study RNA–protein interactions

M Ramanathan, DF Porter, PA Khavari - Nature methods, 2019 - nature.com
Noncoding RNA sequences, including long noncoding RNAs, small nucleolar RNAs, and
untranslated mRNA regions, accomplish many of their diverse functions through direct …

RNA–protein interactions in vivo: global gets specific

ML Änkö, KM Neugebauer - Trends in biochemical sciences, 2012 - cell.com
RNA-binding proteins (RBPs) impact every process in the cell; they act as splicing and
polyadenylation factors, transport and localization factors, stabilizers and destabilizers …

RNA–protein interactions: an overview

A Re, T Joshi, E Kulberkyte, Q Morris… - RNA sequence, structure …, 2014 - Springer
RNA binding proteins (RBPs) are key players in the regulation of gene expression. In this
chapter we discuss the main protein–RNA recognition modes used by RBPs in order to …

Advances in the characterization of RNA‐binding proteins

D Marchese, NS de Groot… - Wiley …, 2016 - Wiley Online Library
From transcription, to transport, storage, and translation, RNA depends on association with
different RNA‐binding proteins (RBPs). Methods based on next‐generation sequencing and …

Dynamics in multi-domain protein recognition of RNA

CD Mackereth, M Sattler - Current opinion in structural biology, 2012 - Elsevier
Protein–RNA interactions play essential roles in gene regulation and RNA metabolism.
While high-resolution structures have revealed principles of RNA recognition by individual …

A brave new world of RNA-binding proteins

MW Hentze, A Castello, T Schwarzl… - Nature reviews Molecular …, 2018 - nature.com
RNA-binding proteins (RBPs) are typically thought of as proteins that bind RNA through one
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …