Extracellular vesicles derived from neural stem cells, astrocytes, and microglia as therapeutics for easing TBI-induced brain dysfunction
C Hering, AK Shetty - Stem cells translational medicine, 2023 - academic.oup.com
Extracellular vesicles (EVs) derived from neural stem cells (NSC-EVs), astrocytes (ADEVs),
and microglia (MDEVs) have neuroregenerative properties. This review discusses the …
and microglia (MDEVs) have neuroregenerative properties. This review discusses the …
Extracellular vesicles mediate neuroprotection and functional recovery after traumatic brain injury
The lack of effective therapies for moderate-to-severe traumatic brain injuries (TBIs) leaves
patients with lifelong disabilities. Neural stem cells (NSCs) have demonstrated great …
patients with lifelong disabilities. Neural stem cells (NSCs) have demonstrated great …
Mesenchymal stem cell-derived extracellular vesicles as a cell-free therapy for traumatic brain injury via neuroprotection and neurorestoration
Y Xiong, A Mahmood, M Chopp - Neural Regeneration Research, 2024 - journals.lww.com
Traumatic brain injury is a serious and complex neurological condition that affects millions of
people worldwide. Despite significant advancements in the field of medicine, effective …
people worldwide. Despite significant advancements in the field of medicine, effective …
Extracellular vesicles improve post-stroke neuroregeneration and prevent postischemic immunosuppression
Although the initial concepts of stem cell therapy aimed at replacing lost tissue, more recent
evidence has suggested that stem and progenitor cells alike promote postischemic …
evidence has suggested that stem and progenitor cells alike promote postischemic …
[HTML][HTML] Stem cell-derived extracellular vesicle therapy for acute brain insults and neurodegenerative diseases
OY Bang, JE Kim - BMB reports, 2022 - ncbi.nlm.nih.gov
Stem cell-based therapy is a promising approach for treating a variety of disorders, including
acute brain insults and neurodegenerative diseases. Stem cells such as mesenchymal stem …
acute brain insults and neurodegenerative diseases. Stem cells such as mesenchymal stem …
Effects of neural stem cell‐derived extracellular vesicles on neuronal protection and functional recovery in the rat model of middle cerebral artery occlusion
M Mahdavipour, G Hassanzadeh… - Cell biochemistry …, 2020 - Wiley Online Library
Stroke imposes a long‐term neurological disability with limited effective treatments available
for neuronal recovery. Transplantation of neural stem cells (NSCs) is reported to improve …
for neuronal recovery. Transplantation of neural stem cells (NSCs) is reported to improve …
Extracellular vesicles as therapeutics for brain injury and disease
Extracellular vesicles (EVs) are gaining tremendous importance in comprehending central
nervous system (CNS) function and treating neurological disorders because of their role in …
nervous system (CNS) function and treating neurological disorders because of their role in …
Extracellular vesicles derived from neural progenitor cells––a preclinical evaluation for stroke treatment in mice
X Zheng, L Zhang, Y Kuang, V Venkataramani… - Translational stroke …, 2021 - Springer
Stem cells such as mesenchymal stem cells (MSCs) enhance neurological recovery in
preclinical stroke models by secreting extracellular vesicles (EVs). Since previous reports …
preclinical stroke models by secreting extracellular vesicles (EVs). Since previous reports …
MSCs-derived exosomes and neuroinflammation, neurogenesis and therapy of traumatic brain injury
Y Yang, Y Ye, X Su, J He, W Bai, X He - Frontiers in cellular …, 2017 - frontiersin.org
Exosomes are endosomal origin membrane-enclosed small vesicles (30–100 nm) that
contain various molecular constituents including proteins, lipids, mRNAs and microRNAs …
contain various molecular constituents including proteins, lipids, mRNAs and microRNAs …
Neural stem cell-derived small extracellular vesicles attenuate apoptosis and neuroinflammation after traumatic spinal cord injury by activating autophagy
Y Rong, W Liu, J Wang, J Fan, Y Luo, L Li, F Kong… - Cell death & …, 2019 - nature.com
Spinal cord injury (SCI) can cause severe irreversible motor dysfunction and even death.
Neural stem cell (NSC) transplantation can promote functional recovery after acute SCI in …
Neural stem cell (NSC) transplantation can promote functional recovery after acute SCI in …
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