Purpose: Cancer is a multigene disease which arises as a result of mutational and
epigenetic changes coupled with activation of complex signaling networks. The use of …

The last decade has witnessed an emerging role for molecular or biochemical markers
indicating a specific cellular mechanism or tissue function, often called 'biomarkers' …

Cancer is a group of diseases characterized by the uncontrolled growth and spread of
abnormal cells and oncology is a branch of medicine that deals with tumors. The last decade …

In spite of advances in diagnostics and therapeutics, cancer remains the second leading
cause of death in the US Successful cancer treatment depends not only on better therapies …

Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer,
occurrence of cancer, or patient outcome. They may include germline or somatic genetic …

Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …

Cancer is one of the major public health problems worldwide representing the leading
cause of morbidity and mortality in industrialized countries. To reduce cancer morbidity and …

Biomarkers provide a powerful and dynamic approach to understanding the spectrum of
malignancies with applications in observational and analytic epidemiology, randomized …

Despite remarkable progress in proteomic methods, including improved detection limits and
sensitivity, these methods have not yet been established in routine clinical practice. The …

Diagnostic detection and measurement of cancer disease progression are essential
elements for successful cancer disease management. The early stages of cancer …