Hypercobalaminemia (high serum vitamin B12 levels) is a frequent and underestimated
anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, reflecting a …

Vitamin B12 (cobalamin) is an essential cofactor for two metabolic pathways. It is obtained
principally from food of animal origin. Cobalamin becomes bioavailable through a series of …

It is well-established that more than 8% of patients examined for vitamin B12 deficiency
unexpectedly have increased plasma levels of the vitamin, but so far there are no guidelines …

Although cobalamin (vitamin B12) was isolated almost 60 years ago, its biochemical,
physiologic and neurologic effects remain incompletely defined. New observations suggest …

Elevated levels of serum cobalamin may be a sign of a serious, even life-threatening,
disease. Hematologic disorders like chronic myelogeneous leukemia, promyelocytic …

The authors' objective, with this study, was to determine the use in routine clinical practice of
the cobalamin serum assay in evaluating patients suspected of having cobalamin …

The Journal of Family Practice, Vol. 41, No. 6 (Dec), 1995 shortcomings of the various tests.
Current state-of-theart testing uses serum cobalamin levels as a screening test and serum or …

Abstract Cobalamin (Cbl, vitamin B12) consists of a corrinoid structure with cobalt in the
centre of the molecule. Neither humans nor animals are able to synthesize this vitamin …

Background There is an urgent need for proper utilization of laboratory markers to diagnose
vitamin B12 deficiency that should reduce false negative cases. We worked out a diagnostic …

Vitamin B12 (cobalamin) deficiency is a common cause of macrocytic anemia and has been
implicated in a spectrum of neuropsychiatric disorders. The role of B12 deficiency in …