In humans, dopamine neurotransmission is influenced by functional polymorphisms in the
dopamine transporter (DAT 1) and catechol-O-methyltransferase (COMT) genes. Here, we …

Reward processing depends critically on dopaminergic neurotransmission in the ventral
striatum. The common polymorphism val158met of catechol-O-methyltransferase (COMT) …

People's sensitivity to reinforcing stimuli such as monetary gains and losses shows a wide
interindividual variation that might in part be determined by genetic differences. Because of …

Reward processing depends on dopaminergic neurotransmission and is modulated by
factors affecting dopamine (DA) reuptake and degradation. We used fMRI and a guessing …

The objective of the study was to test the hypotheses that humans with genotypes putatively
associated with low dopamine (DA) signaling capacity, including the TaqIA A1 allele, DRD2 …

BACKGROUND: Interindividual variability in the processing of reward might be partially
explained by genetic differences in the dopamine system. Here, we study whether brain …

Functional polymorphisms in the catechol-O-methyltransferase (COMT) and the dopamine
transporter (DAT) genes modulate dopamine inactivation, which is crucial for determining …

The impact of individual differences on human reward processing has been a focus of
research in recent years, particularly, as they are associated with a variety of …

Individual differences in traits such as impulsivity involve high reward sensitivity and are
associated with risk for substance use disorders. The ventral striatum (VS) has been widely …

Two limiting factors of dopamine activity are the catechol-o-methyltransferase (COMT) and
the dopamine transporter (DAT), which terminate dopamine activity by degradation and …