Serum metabolic profile characteristics of offspring rats before and after birth caused by prenatal caffeine exposure

G Chen, Q Zhang, C Ai, S Huang, H Zhang, X Guo… - Toxicology, 2019 - Elsevier
Epidemiological investigations have confirmed that prenatal caffeine intake could increase
the incidence rate of intrauterine growth retardation (IUGR) and multiple diseases after birth …

Influencing factors, underlying mechanism and interactions affecting hypercholesterolemia in adult offspring with caffeine exposure during pregnancy

Y Guo, H Luo, Y Wu, J Magdalou, L Chen… - Reproductive Toxicology, 2018 - Elsevier
Epidemiological surveys suggest that adult hypercholesterolemia has an intrauterine origin
and exhibits gender differences. Our previous study demonstrated that adult rats with …

Effects of prenatal caffeine exposure on glucose homeostasis of adult offspring rats

H Kou, G Wang, L Pei, L Zhang, C Shi, Y Guo… - The Science of …, 2017 - Springer
Epidemiological evidences show that prenatal caffeine exposure (PCE) could induce
intrauterine growth retardation (IUGR). The IUGR offspring also present glucose intolerance …

[HTML][HTML] Metabolic response of adult male offspring rats to prenatal caffeine exposure

I Mastroleon, LM Korou, V Pergialiotis, IS Vlachos… - Cureus, 2020 - ncbi.nlm.nih.gov
Caffeine is the most widely consumed psychoactive substance, with recommendations from
health associations and regulatory bodies for limiting caffeine consumption during …

Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet

J Li, H Luo, Y Wu, Z He, L Zhang, Y Guo, L Ma… - Toxicology and Applied …, 2015 - Elsevier
Prenatal caffeine exposure (PCE) alters the hypothalamic–pituitary–adrenocortical (HPA)
axis-associated neuroendocrine metabolic programming and induces an increased …

Maternal glucocorticoid elevation and associated blood metabonome changes might be involved in metabolic programming of intrauterine growth retardation in rats …

H Kou, Y Liu, G Liang, J Huang, J Hu, Y Yan… - Toxicology and applied …, 2014 - Elsevier
Our previous studies demonstrated that prenatal caffeine exposure causes intrauterine
growth retardation (IUGR), fetuses are over-exposed to high levels of maternal …

Prenatal caffeine ingestion increases susceptibility to pulmonary inflammation in adult female rat offspring

H Liu, L Hou, T Chen, W Qu, S Liu, H Yan, X Wen… - Reproductive …, 2017 - Elsevier
This study aimed to investigate the association between prenatal caffeine ingestion (PCI)
and risk of postnatal pulmonary inflammation. Pregnant Wistar rats were administered 60 …

Can mothers consume caffeine? The issue of early life exposure and metabolic changes in offspring

LL Souza, EG Moura, PC Lisboa - Toxicology Letters, 2024 - Elsevier
Caffeine is a substance with central and metabolic effects. Although it is recommended that
its use be limited during pregnancy, many women continue to consume caffeine. Direct and …

Prenatal caffeine ingestion induces transgenerational neuroendocrine metabolic programming alteration in second generation rats

H Luo, Z Deng, L Liu, L Shen, H Kou, Z He… - Toxicology and applied …, 2014 - Elsevier
Our previous studies have demonstrated that prenatal caffeine ingestion induces an
increased susceptibility to metabolic syndrome with alterations of glucose and lipid …

Prenatal caffeine exposure induced high susceptibility to metabolic syndrome in adult female offspring rats and its underlying mechanisms

L Pei, C Yuan, Y Guo, H Kou, L Xia, L Zhang… - Reproductive …, 2017 - Elsevier
Our previous studies have demonstrated that prenatal caffeine exposure (PCE) induced an
intrauterine programming of hypothalamic–pituitary–adrenal axis (HPAA)-associated …