[HTML][HTML] Transcriptional basis of mouse and human dendritic cell heterogeneity
CC Brown, H Gudjonson, Y Pritykin, D Deep… - Cell, 2019 - cell.com
Dendritic cells (DCs) play a critical role in orchestrating adaptive immune responses due to
their unique ability to initiate T cell responses and direct their differentiation into effector …
their unique ability to initiate T cell responses and direct their differentiation into effector …
[HTML][HTML] Development and function of dendritic cell subsets
A Mildner, S Jung - Immunity, 2014 - cell.com
Classical dendritic cells (cDCs) form a critical interface between innate and adaptive
immunity. As myeloid immune cell sentinels, cDCs are specialized in the sensing of …
immunity. As myeloid immune cell sentinels, cDCs are specialized in the sensing of …
Transcriptional control of dendritic cell development and functions
L Amon, CHK Lehmann, A Baranska, J Schoen… - International review of …, 2019 - Elsevier
Dendritic cells (DCs) are major regulators of adaptive immunity, as they are not only capable
to induce efficient immune responses, but are also crucial to maintain peripheral tolerance …
to induce efficient immune responses, but are also crucial to maintain peripheral tolerance …
[HTML][HTML] Transcriptional regulation of dendritic cell development and function
Dendritic cells (DCs) are sentinel immune cells that form a critical bridge linking the innate
and adaptive immune systems. Extensive research addressing the cellular origin and …
and adaptive immune systems. Extensive research addressing the cellular origin and …
[HTML][HTML] Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice
NE Papaioannou, N Salei, S Rambichler, K Ravi… - Nature …, 2021 - nature.com
Conventional dendritic cells (cDC) are key activators of naive T cells, and can be targeted in
adults to induce adaptive immunity, but in early life are considered under-developed or …
adults to induce adaptive immunity, but in early life are considered under-developed or …
[HTML][HTML] Transcriptional networks driving dendritic cell differentiation and function
Dendritic cells (DCs) are the sentinels of the immune system, sensing a diverse array of
pathogens to stimulate a robust and appropriate immune response. To initiate responses to …
pathogens to stimulate a robust and appropriate immune response. To initiate responses to …
Single-cell transcriptional profiling informs efficient reprogramming of human somatic cells to cross-presenting dendritic cells
FF Rosa, CF Pires, I Kurochkin, E Halitzki… - Science …, 2022 - science.org
Type 1 conventional dendritic cells (cDC1s) are rare immune cells critical for the induction of
antigen-specific cytotoxic CD8+ T cells, although the genetic program driving human cDC1 …
antigen-specific cytotoxic CD8+ T cells, although the genetic program driving human cDC1 …
Human dendritic cell subsets: an update
Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …
haematopoiesis that form an essential interface between the innate sensing of pathogens …
Development, diversity, and function of dendritic cells in mouse and human
DA Anderson, KM Murphy… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
The study of murine dendritic cell (DC) development has been integral to the identification of
specialized DC subsets that have unique requirements for their form and function. Advances …
specialized DC subsets that have unique requirements for their form and function. Advances …
NF-κB–dependent IRF1 activation programs cDC1 dendritic cells to drive antitumor immunity
Conventional type 1 dendritic cells (cDC1s) are critical for antitumor immunity. They acquire
antigens from dying tumor cells and cross-present them to CD8+ T cells, promoting the …
antigens from dying tumor cells and cross-present them to CD8+ T cells, promoting the …