Cochlear gene therapy
LR Lustig, O Akil - Current opinion in neurology, 2012 - journals.lww.com
Cochlear gene therapy : Current Opinion in Neurology Cochlear gene therapy : Current Opinion
in Neurology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts …
in Neurology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts …
Milestones toward cochlear gene therapy for patients with hereditary hearing loss
H Yoshimura, SY Nishio… - Laryngoscope Investigative …, 2021 - Wiley Online Library
A number of genes are reportedly responsible for hereditary hearing loss, which accounts
for over 50% of all congenital hearing loss cases. Recent advances in genetic testing have …
for over 50% of all congenital hearing loss cases. Recent advances in genetic testing have …
Cochlear gene therapy
AK Lalwani, AN Mhatre - Ear and Hearing, 2003 - journals.lww.com
Despite the prevalence of hearing disorders in humans, therapeutic options are limited to
rehabilitation with amplification or implantable electronic prosthesis. In contrast to …
rehabilitation with amplification or implantable electronic prosthesis. In contrast to …
Advances in cochlear gene therapies
MJ Klimara, RJH Smith - Current opinion in pediatrics, 2023 - journals.lww.com
Gene therapies for hearing loss are expected to enter clinical trials in the immediate future.
To provide referral for appropriate trials and counseling regarding benefits of genetic …
To provide referral for appropriate trials and counseling regarding benefits of genetic …
Cochlear gene therapy
L Lustig, O Akil - Cold Spring Harbor perspectives …, 2019 - perspectivesinmedicine.cshlp.org
Over 450 million people worldwide suffer from hearing loss, leading to an estimated
economic burden of∼ $750 billion. The past decade has seen significant advances in the …
economic burden of∼ $750 billion. The past decade has seen significant advances in the …
Cellular targeting for cochlear gene therapy
AF Ryan, LM Mullen, JK Doherty - Gene Therapy of Cochlear Deafness, 2009 - karger.com
Gene therapy has considerable potential for the treatment of disorders of the inner ear. Many
forms of inherited hearing loss have now been linked to specific locations in the genome …
forms of inherited hearing loss have now been linked to specific locations in the genome …
Gene therapy for hearing loss
R Omichi, SB Shibata, CC Morton… - Human molecular …, 2019 - academic.oup.com
Sensorineural hearing loss (SNHL) is the most common sensory disorder. Its underlying
etiologies include a broad spectrum of genetic and environmental factors that can lead to …
etiologies include a broad spectrum of genetic and environmental factors that can lead to …
Cochlear gene therapy for sensorineural hearing loss: current status and major remaining hurdles for translational success
W Zhang, SM Kim, W Wang, C Cai, Y Feng… - Frontiers in molecular …, 2018 - frontiersin.org
Sensorineural hearing loss (SNHL) affects millions of people. Genetic mutations play a large
and direct role in both congenital and late-onset cases of SNHL (eg, age-dependent hearing …
and direct role in both congenital and late-onset cases of SNHL (eg, age-dependent hearing …
Genetic therapies for hearing loss: Accomplishments and remaining challenges
S Taiber, KB Avraham - Neuroscience letters, 2019 - Elsevier
More than 15 years have passed since the official completion of the Human Genome
Project. Predominantly due to this project, over one hundred genes have now been linked to …
Project. Predominantly due to this project, over one hundred genes have now been linked to …
Gene therapy for genetic mutations affecting non-sensory cells in the cochlea
L Zhang, X Wu, X Lin - Hearing Research, 2020 - Elsevier
Congenital hearing loss (HL) affects about 1 in every 500 infants. Among those affected
more than half are caused by genetic mutations. According to the cellular sites affected by …
more than half are caused by genetic mutations. According to the cellular sites affected by …