Long noncoding RNA just proximal to X‐inactive specific transcript facilitates aerobic glycolysis and temozolomide chemoresistance by promoting stability of PDK1 …
XD Li, MJ Wang, JL Zheng, YH Wu, X Wang… - Cancer …, 2021 - Wiley Online Library
Improving the chemotherapy resistance of temozolomide (TMZ) is of great significance in the
treatment of glioblastoma multiforme (GBM). Long non‐coding RNA just proximal to the X …
treatment of glioblastoma multiforme (GBM). Long non‐coding RNA just proximal to the X …
LncRNA-XIST interacts with miR-29c to modulate the chemoresistance of glioma cell to TMZ through DNA mismatch repair pathway
P Du, H Zhao, R Peng, Q Liu, J Yuan, G Peng… - Bioscience …, 2017 - portlandpress.com
Temozolomide (TMZ) is the most commonly used alkylating agent in glioma chemotherapy.
However, growing resistance to TMZ remains a major challenge for clinicians. Recent …
However, growing resistance to TMZ remains a major challenge for clinicians. Recent …
lncRNA XLOC013218 promotes cell proliferation and TMZ resistance by targeting the PIK3R2‐mediated PI3K/AKT pathway in glioma
The discovery of long noncoding RNAs (lncRNAs) has improved the understanding of
development and progression in various cancer subtypes. However, the role of lncRNAs in …
development and progression in various cancer subtypes. However, the role of lncRNAs in …
[HTML][HTML] Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin
F Sun, Y Liu, T Gong, Q Pan, T Xiang, J Zhao… - Cell Death & …, 2021 - nature.com
Most patients with hepatocellular carcinoma (HCC) are in the middle or advanced stage at
the time of diagnosis, and the therapeutic effect is limited. Therefore, this study aimed to …
the time of diagnosis, and the therapeutic effect is limited. Therefore, this study aimed to …
[HTML][HTML] Long non-coding RNAs in multidrug resistance of glioblastoma
Glioblastoma, also known as glioblastoma multiforme, is the most aggressive brain tumor in
adults. Despite the huge advance in developing novel therapeutic strategies for patients with …
adults. Despite the huge advance in developing novel therapeutic strategies for patients with …
Long non-coding RNA JPX correlates with poor prognosis and tumor progression in non-small-cell lung cancer by interacting with miR-145-5p and CCND2
M Jin, J Ren, M Luo, Z You, Y Fang, Y Han, G Li… - …, 2020 - academic.oup.com
Emerging studies have shown that the aberrant expression and function of long non-coding
RNAs (lncRNAs) are involved in carcinogenesis and the development of various cancers …
RNAs (lncRNAs) are involved in carcinogenesis and the development of various cancers …
[HTML][HTML] JNK contributes to temozolomide resistance of stem-like glioblastoma cells via regulation of MGMT expression
M Okada, A Sato, K Shibuya… - International …, 2014 - spandidos-publications.com
While elimination of the cancer stem cell population is increasingly recognized as a key to
successful treatment of cancer, the high resistance of cancer stem cells to conventional …
successful treatment of cancer, the high resistance of cancer stem cells to conventional …
Knockdown of long noncoding RNA H19 sensitizes human glioma cells to temozolomide therapy
P Jiang, P Wang, X Sun, Z Yuan, R Zhan… - OncoTargets and …, 2016 - Taylor & Francis
Temozolomide (TMZ) is commonly used in glioma chemotherapy. However, a great clinical
challenge for TMZ is chemoresistance. H19 transcripts are recognized as long noncoding …
challenge for TMZ is chemoresistance. H19 transcripts are recognized as long noncoding …
[HTML][HTML] MicroRNA-101 reverses temozolomide resistance by inhibition of GSK3β in glioblastoma
T Tian, M Mingyi, X Qiu, Y Qiu - Oncotarget, 2016 - ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM) is a chemotherapy-resistant brain tumor with limited
treatment options. Temozolomide (TMZ), an alkylating agent, is a front-line …
treatment options. Temozolomide (TMZ), an alkylating agent, is a front-line …
[HTML][HTML] PDIA3P1 promotes Temozolomide resistance in glioblastoma by inhibiting C/EBPβ degradation to facilitate proneural-to-mesenchymal transition
Z Gao, J Xu, Y Fan, Y Qi, S Wang, S Zhao… - Journal of Experimental …, 2022 - Springer
Background Resistance to temozolomide (TMZ) is a major obstacle to preventing
glioblastoma (GBM) recurrence after surgery. Although long noncoding RNAs (lncRNAs) …
glioblastoma (GBM) recurrence after surgery. Although long noncoding RNAs (lncRNAs) …