[HTML][HTML] Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ1-42-induced Alzheimer's disease mice and glutamate-injured …

S Yang, Z Xie, T Pei, Y Zeng, Q Xiong, H Wei, Y Wang… - Chinese Medicine, 2022 - Springer
Background Alzheimer's disease (AD) is a neurodegenerative disease. Ferroptosis plays a
critical role in neurodegenerative diseases. Nuclear factor E2-related factor 2 (Nrf2) is …

[HTML][HTML] Salidroside alleviates cognitive impairment by inhibiting ferroptosis via activation of the Nrf2/GPX4 axis in SAMP8 mice

S Yang, L Wang, Y Zeng, Y Wang, T Pei, Z Xie, Q Xiong… - Phytomedicine, 2023 - Elsevier
Background Alzheimer's disease (AD) is a neurogenerative disease and remains no
effective method for stopping its progress. Ferroptosis and adaptive immunity have been …

[HTML][HTML] Astragaloside IV mitigates cerebral ischaemia-reperfusion injury via inhibition of P62/Keap1/Nrf2 pathway-mediated ferroptosis

L Wang, C Liu, L Wang, B Tang - European Journal of Pharmacology, 2023 - Elsevier
Cerebral ischaemia-reperfusion injury (CIRI) is a critical component of ischaemic stroke
pathogenesis. Ferroptosis contributes to and aggravates CIRI, whereas the P62/Kelch-like …

Extract of Naotaifang, a compound Chinese herbal medicine, protects neuron ferroptosis induced by acute cerebral ischemia in rats

B Lan, J Ge, S Cheng, X Zheng, J Liao, C He… - Journal of Integrative …, 2020 - Elsevier
Objective Our previous research showed that Naotaifang (a compound traditional Chinese
herbal medicine) extract (NTE) has clinically beneficial effects on neurological improvement …

Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice

Y Liu, Y Mi, Y Wang, Q Meng, L Xu, Y Liu, D Zhou… - Phytomedicine, 2023 - Elsevier
Background Ischemic stroke (IS) is considered as a serious cerebral vascular disease.
Ferroptosis is a novel type of regulated cell death (RCD), that closely related to the …

N2L, a novel lipoic acid-niacin dimer, attenuates ferroptosis and decreases lipid peroxidation in HT22 cells

W Peng, Z Zhu, Y Yang, J Hou, J Lu, C Chen, F Liu… - Brain Research …, 2021 - Elsevier
Ferroptosis, a new type of programmed cell death discovered in recent years, plays an
important role in many neurodegenerative diseases. N2L is a novel lipoic acid-niacin dimer …

[HTML][HTML] Forsythoside a mitigates alzheimer's-like pathology by inhibiting ferroptosis-mediated neuroinflammation via Nrf2/GPX4 axis activation

C Wang, S Chen, H Guo, H Jiang, H Liu… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Ferroptosis and neuroinflammation play crucial roles in Alzheimer's disease (AD)
pathophysiology. Forsythoside A (FA), the main constituent of Forsythia suspensa (Thunb.) …

Dimethyl fumarate improves cognitive deficits in chronic cerebral hypoperfusion rats by alleviating inflammation, oxidative stress, and ferroptosis via NRF2/ARE/NF-κB …

N Yan, Z Xu, C Qu, JJ Zhang - International Immunopharmacology, 2021 - Elsevier
Cerebrovascular disease and its risk factors cause persistent decrease of cerebral blood
flow, chronic cerebral hypoperfusion (CCH) is the major foundation of vascular cognitive …

[HTML][HTML] Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhage via Nrf2/HO-1 signaling pathway

Z Liu, Z Zhou, P Ai, C Zhang, J Chen… - Frontiers in …, 2022 - frontiersin.org
Subarachnoid hemorrhage (SAH) is a severe type of stroke featuring exceptionally high rate
of morbidity and mortality due to the lack of effective management. Ferroptosis can be …

[HTML][HTML] Ferroptosis, a potential therapeutic target in Alzheimer's disease

K Chen, X Jiang, M Wu, X Cao, W Bao… - Frontiers in Cell and …, 2021 - frontiersin.org
Cell death is a common phenomenon in the progression of Alzheimer's disease (AD).
However, the mechanism of triggering the death of neuronal cells remains unclear …